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InPrePPI is a web-based application for
the prediction of protein-protein
interactions (PPIs) using one of the four
genomic context based methods
(Phylogenetic profile method, Gene cluster
method, Gene fusion method, and Gene
neighbor method) or an integration method
(InPrePPI) based on these four methods. In
InPrePPI, it first calculates a score for
each protein-protein pair predicted by the
four genomic context based methods and
then obtains an integrated score using an
optimal weight. Based on the integrated
score, InPrePPI extracts the PPIs with
high confidence from all of the predicted
protein pairs. These PPIs may be further
validated by experimental approaches. The
user may select to predict PPIs using one
of the four methods or InPrePPI. The user
may set or modify parameters such as
BLASTP E-value, target organism, or a list
of reference organisms.
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