BALF, obtained during fiber-optic bronchoscopy, is a biofluid mirroring the expression of normally secreted pulmonary proteins and the products of activated cells and destructive processes. BALF is presently the most common way of sampling the components of the epithelial lining fluid and the most faithful reflect of the protein composition of the pulmonary airways. The characterization of the proteome within this compartment provides an opportunity to establish temporal and prognostic indicators of airway diseases.
Detection and identification of human bronchoalveolar lavage proteins using narrow-range immobilized pH gradient DryStrip and the paper bridge sample application method
Rapid Proteome Analysis of Bronchoalveolar Lavage Samples of Lifelong Smokers and Never-Smokers by Micro-Scale Liquid Chromatography and Mass Spectrometry