BIOSINO 我国的核酸序列公共数据库

EMBL - EMBL Nucleotide sequence database (EBI) *

GenBank - GenBank Nucleotide Sequence database (NCBI) *

DDBJ - DNA Data Bank of Japan *

dbEST - Database of Expressed Sequence Tags  (NCBI)

dbSTS - Database of Sequence Tagged Sites (NCBI)

2.基因组及相关数据库  Genomic Databases

GenomeWeb(HGMP) - A catalogue of useful Web sites for Genomics with a set of collections of genome databases 

GSDB - Genome Sequence database (NCGR)

GOLD - Genomes On-line db

一些数据库的直接链接

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DOGS - Database of Genome Sizes  

Genomics web site (John Wiley & Sons Ltd) (The Genomics website at Wiley is a new and DYNAMIC resource for the genomics community, offering FREE special feature articles and new information EACH MONTH.)

HUGO - HUman Genome Organization

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3.核酸三维结构数据库

NDB - Nucleic Acid Databank (3D structures)

BNASDB - Nucleic acid structure db from University of Pune

4.其他

AsDb - Aberrant Splicing db

ACUTS - Ancient conserved untranslated DNA sequences db

Codon Usage Db  - The frequency of codon use in each organism is made searchable through this World Wide Web site.

EPD - Eukaryotic Promoter db

HOVERGEN - Homologous Vertebrate Genes db

IMGT - ImMunoGeneTics db [Mirror at EBI]

ISIS - Intron Sequence and Information System

RDP - Ribosomal db Project

gRNAs db - Guide RNA db

PLACE - Plant cis-acting regulatory DNA elements db

PlantCARE - Plant cis-acting regulatory DNA elements db

sRNA db - Small RNA db

ssu rRNA - Small ribosomal subunit db

lsu rRNA - Large ribosomal subunit db

5S rRNA - 5S ribosomal RNA db

tmRNA Website

tmRDB - tmRNA dB

tRNA - tRNA compilation from the University of Bayreuth

uRNADB - uRNA db

RNA editing - RNA editing site

RNAmod db - RNA modification db

TelDB - Multimedia Telomere Resource

TRADAT - TRAnscription Databases and Analysis Tools

Subviral RNA db - Small circular RNAs db (viroid and viroid-like)

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MPDB - Molecular probe db

OPD - Oligonucleotide probe db

VectorDB - Vector sequence db

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Transgenics

Cre Transgenic Database - Cre transgenic mouse lines

Transgenic/Targeted Mutation Database - Information on transgenic animals and targeted mutations

　蛋白质及其相关数据库

SWISS-PROT - SWISS-PROT annotated protein sequence db

PIR-international -The Protein Information Resource (protein sequence)

MIPS - Martinsried institute for protein sequence and homology data and yeast genome information

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PROSITE - PROSITE dictionary of protein sites and patterns

InterPro - Integrated Resources of Proteins Domains and Functional Sites

BLOCKS - BLOCKS db

DOMO - Protein domain db (Automatically generated)

Pfam - Protein families db (HMM derived) [Mirror at Sanger]

PRINTS - Protein Motif fingerprint db

ProDom - Protein domain db (Automatically generated)

PROTOMAP - An automatic hierarchical classification of SWISS-PROT proteins

SBASE - SBASE domain db (Protein domain sequence library)

SMART - Protein signalling and extracellular domain patterns (Simple Modular Architecture Research Tool)

ProClass - Protein sequence alignments and curation of protein families

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Kabat - Kabat db of protein of immunological interest

PMD - Protein Mutant db

2.蛋白质三维结构和相关数据库

PDB - Protein Data Bank [Mirrors in EBI]

BioMagResBank - Repository for data on proteins, peptides, and nucleic acids from NMR spectroscopy

SWISS-MODEL Repository - Automatically generated protein models db

ModBase - Db of comparative protein structure models

CATH - UCL BSM structural classification of proteins

SCOP - Structural classification of proteins [Mirror at USA | Israel | Singapore | Australia]

Mol_R_Us - Molecules R Us, browser for PDB

BMM Domain Server - Biomolecular Modelling Laboratory (ICRF) protein domain server

PRESAGE - Collaborative resource for structural genomics

ReLiBase - Receptor/ligand complexes db [Mirror in USA]

TOPS - Protein topology atlas

CCDC - Cambridge Crystallographic Data Center (Cambridge Stuctural Db (CSD))

HSSP - Homology-derived secondary structure of proteins db

SWISS-3DIMAGE - 3D images of proteins and other biological macromolecules

BioImage - Biological image db (contains imaging data on macromolecules)

3.蛋白质二维凝胶电泳数据库

WORLD-2DPAGE - A complete index of 2D-PAGE db and servers

Phoretix links - Phoretix page of links to 2D gel db

4.信号传导及蛋白质-蛋白质相互作用相关数据库

DIP - Db of Interacting Proteins

INTERACT - Protein-Protein interaction db

ProNet - Protein-Protein interaction db

CANSITE - Signal Transduction's Web

SPAD - Signaling pathway db

CSNDB - Cell Signaling Networks db

5.DNA和蛋白质相互作用数据库

DPInteract - DNA-Proteins interactions db

Acetylcholinesterases

ALDH - Aldehyde dehydrogenase gene superfamily db

Aminoacyl-tRNA synthetases in SWISS-PROT - List of aminoacyl-tRNA synthetases in SWISS-PROT

AARSDB - Aminoacyl-tRNA synthetases db

Allergens in SWISS-PROT - Nomenclature and index of allergens in SWISS-PROT

AMSDb - Antimicrobial sequences db

Antibody resource page - Links to antibody related Web resources

Australian venom and toxin db

Bacillus thuringiensis toxin specificity db

TFII - Basal transcription factors

Blood group antigens in SWISS-PROT

BCGD - Breast cancer genes db from MBCR

BRENDA - Db of enzyme functional data

EF-hand CaBP - EF-hand calcium-binding proteins db

CAZy - Carbohydrate-Active enZYmes Web site

CBS domain - Cystathionine Beta Synthase domain WWW page

CD antigens in SWISS-PROT - Nomenclature for surface proteins of human leucocytes (CD)

CD antigens in PROW - Database on information about CD antigens

Chaperonin - Information on GroEL and GroES chaperonins

Conotoxins - Information on conotoxins from a Web site on cone shells

Cytokines Web - Structure and function of cytokines and their receptors

COPE - Cytokines On-line Pathfinder Encyclopedia [Mirror in Israel]

dbCFC - Cytokine family cDNA db

R&D Systems' Cytokine Source Book

DExH/D protein family db

ENZYME - Enzymes nomenclature db

Worthington enzyme manual

Eph - Eph receptor tyrosine kinases and their ligands (ephrins) resource

EpoDB - Erythropoiesis gene expression db (Epo GED)

ESTHER - Esterases and alpha/beta hydrolase enzymes

Expansins web site

Modules - Extracellular proteins modules (domains)

FADPNR - FAD-dependent pyridine nucleotide oxidoreductases

Flavodoxins

FlyNets - Db of molecular interactions in Drosophila melanogaster

FYVE finger domain

GABAagent - GABA receptors WWW site

Globin - Globin gene server

Glucoamylases

Glycosyl hydrolases in SWISS-PROT - Nomenclature and index of glycosyl hydrolases in SWISS-PROT

7TM in SWISS-PROT - List of G protein coupled receptors in SWISS-PROT

GCRDb - G protein-coupled receptor db

GPCRDB - G protein-coupled receptor db (7TM) at EMBL

ORDB - Olfactory receptor db

GRAP - G protein coupled receptors family A mutants db

GRR - Glucocorticoid receptor resource

Glycosyltransferases - A guide to cloned glycosyltransferases

GnRH - Gonadotropin-releasing hormones (GnRH) family

GyrB - GyrB protein

Yeast RNA helicases

Histone - Histones db

HIVdb - HIV protease db

HotMolecBase - Molecules (mainly proteins) that are promising targets for medical applications

Homeobox - Homeobox domain proteins resource

HOX-Pro - Homeobox genes db

Hox proteins in SWISS-PROT - Vertebrate homeotic Hox proteins: nomenclature and index of SWISS-PROT entries

Labial - Homeobox genes, labial family

HSP100 - HSP100/ClpAB family of chaperones

InBase - Inteins db from the New England Biolabs

Integrins

ICN - The Ion Channel Network

KEGG - Kyoto Encyclopedia of Genes and Genomes

Kinesin - Kinesin motor proteins

Klotho - Biochemical compounds declarative db

LGIC - Ligand Gated Ion Channel subunit db

LED - Lipase Engineering Database

MDB - Metalloprotein Site Database and Browser

Metallothioneins in SWISS-PROT - Nomenclature and index of metallothioneins in SWISS-PROT

MT - Metallothioneins

MHCPEP - MHC binding peptides db

SYFPEITHI - MHC ligands and peptide motifs db

Mitochondrial carriers pages from Nelson's lab

MitoPick - Mitochondrial NADH-ubiquinone reductase (complex I) web site

MRR - Mineralocorticoid receptor resource

Mutator - Transposases, Mutator family

MutBase - Mutation spectra db (Db on mutants of several bacterial and mammalian genes)

MutS - MutS family

Neurotrophic factors

NucleaRDB - Federated db on nuclear receptors

P450 pages from Nelson's lab

P450 - Directory of P450-containing systems

IARC p53 db - IARC db of somatic p53 mutations

PDZ domain - PDH/DHR domain WWW page

PDE - Phosphodiesterases

Peroxidases

Plant Peroxidases

Peptidases in SWISS-PROT - Nomenclature and index of peptidases in SWISS-PROT

MEROPS - Peptidase db

Prolysis - Proteases and inhibitors server

Protein Degradation Resource

PLACE - Plant cis-acting regulatory DNA elements db

PlantCARE - Plant cis-acting regulatory DNA elements db

PKR - Protein Kinase Resource

PatBase - P-type ATPase db

PPAR - Peroxisome Proliferator-Activated Receptor resource

PPDB - Phosphoprotein db

Proteoglycans

Phytochromes - Computer analysis of phytochrome sequences

RecA - RecA protein

REBASE - Restriction enzymes and methylases db

Restriction enzymes/methylases in SWISS-PROT - List of restriction enzymes and methylases in SWISS-PROT

Ribosomal proteins in SWISS-PROT - Families and index of ribosomal proteins in SWISS-PROT

Ribosomal proteins - Analysis of R proteins by Nikos Kyrpides

RNase P - Ribonuclease P db

SRPDB - Signal Recognition Particle db

SNF2 - SNF2 family

TRR - Thyroid hormone receptors resource

Topoisomerases - Type I and II topoisomerases

TRANSFAC - Transcription factors db

TRANSPATH - Signal Transduction Browser

Transport Classification System - from Milton Saier

UDP Glucuronosyltransferases

V BASE - Directory of human V gene sequences (Immunoglobulin germline variable region)

VDRR - Vitamin D receptor resource

WD-repeat - WD-repeat proteins family

WIT - 'What is There' metabolic models db

WormPep - C.elegans proteins db

YTPdb - Yeast Transport Protein db

糖类相关数据库

GlycoSuiteDB - Db of glycan structures

TGN - The Glycoscience Network

FCCA - Forum Carbohydrates Coming of Age

CARBHYD - Carbohydrate information WWW sites

Monosacharide browser - Space filling Fischer projection for monosaccharides

蛋白质翻译后修饰相关数据库

O-GlycBase - O-glycosylated proteins db

PhosphoBase - Phosphorylation sites db

RESID - Db of Amino Acid Modifications

基因表达数据库

ASDB - Protein products and expression patterns of alternatively-spliced genes

Axeldb - Gene expression in Xenopus

BodyMap - Human and mouse gene expression data

EpoDB - Genes expressed in vertebrate RBC

FlyView - Drosophila development and genetics

Gene Expression Database (GXD) - Mouse gene expression and genomics

Kidney Development Database - Kidney development and gene expression

MAGEST - Ascidian (Halocynthia roretzi) gene expression patterns

Mouse Atlas and Gene Expression Database - Spatially-mapped gene expression data

PEDB - Normal and aberrant prostate gene expression

Tooth Development Database - Gene expression in dental tissue

TRIPLES - TRansposon-Insertion Phenotypes, Localization and Expression in Saccharomyces

人类基因突变及疾病相关数据库

SVD - Sequence variation db

HGBASE - Human Genic Bi-Allelic Sequences db

The SNP consortium

dbSNP - Human single nucleotide polymorphism (SNP) db

List of mutation databases from IMT (Finland)

Alpha-glucosidase - Information about human acid alpha-glucosidase (GSD-II)

AR mutations - Human androgen receptor mutation db

Antithrombin mutation db

Asthma and Allergy gene db

BIOMDB - Db of mutations causing tetrahydrobiopterin deficiencies

BLMbase - Human BLM mutation db (Bloom snydrom)

BTKbase - Human BTK mutation db (X-linked agammaglobulinemia)

CD40Lbase - Human CD40 ligand mutation db

COL1/3 mutation - Human Type I and III collagen mutation db

CFTR mutation - Human cystic fibrosis mutation db (CFTR)

EMD db - Human Emerin (EMD) mutation db (Emery-Dreifuss muscular dystrophy)

KMeyeDB - Eye disease genes db

FVII mutation - Human Factor VII mutation db

HAMSTeRS - Human Factor VIII mutation db (Haemophilia A)

HAeMB - Human Factor IX mutation db (Haemophilia B)

FBN1 mutation - Human fibrillin 1 mutation db (Marfan syndrome)

G6PD - Human G6PD deficiency resource

Galt mutation - Human galactose-1-phosphate uridylyltransferase mutation db (Galactosemia)

HEXAdb - Human Hexosaminidase A mutation db (Tay-sachs disease)

IL2RGbase - Human IL2RG (Interleukin-2 receptor gamma) mutation db (X-SCID)

L1CAM mutation - Human L1CAM mutation db

LDLR mutation - Human LDLR mutation db (Familial hypercholesterolemia)

LQTSdb - Long QT syndrome db

NCF1base - Human NCF1 mutation db

NCF2base - Human NCF2 mutation db

Neuromuscular diseases web site

NCL - Neuronal Ceroid Lipofuscinoses mutation db

OTCase - Human ornithine transcarbamylase (OTCase) website

Cytochrome P450 alleles nomenclature

p53 mutation db - University of Tokyo p53 mutation db

Germline p53 mutation db - University of Prague db of germline p53 mutations

PAHdb - Human phenylalanine hydroxylase (PAH) mutation db

PAX6 mutation - Human PAX6 mutation db

Prion - Prion and prion disease web site

RAG1base - Human RAG1 mutation db

RAG2base - Human RAG2 mutation db

RB1base - Human retinoblastoma-associated protein (RB) mutation db

RetNet - Retinal Information Network

Retina International Scientific Newsletter - Information on Retinal genes, proteins and diseases

TSC - TSC (TSC1/TSC2) variation db

TSC2 - Cardiff-Rotterdam Tuberous Sclerosis (TS) db (Tuberin; TSC2)

TGDB - Tumor gene db

VMD2 mutation - Human VMD2 mutation db

vWF mutation - Human von Willebrand factor (vWF) mutation db

WRN - Human WRN mutation db (Warner disease)

WT1 mutation - Human WT1 mutation db

X-ALD mutation - Human ABCD1 mutation db