Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
stats1
stats2
stats3
stats4
40433 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A46924 | 34116071 | Toxicol Appl Pharmacol | Liver-specific Nrf2 deficiency accelerates ethanol-induced lethality and hepatic injury in vivo. | 2021 | Details |
| A46925 | 34068838 | Nutrients | Markers of Intestinal Permeability Are Rapidly Improved by Alcohol Withdrawal in Patients with Alcohol-Related Liver Disease. | 2021 | Details |
| A46926 | 34066517 | Cells | Chronic Alcohol Exposure of Cells Using Controlled Alcohol-Releasing Capillaries. | 2021 | Details |
| A46927 | 34044170 | Bone | Mechano-structural alteration in proximal femora of individuals with alcoholic liver disease: Implications for increased bone fragility. | 2021 | Details |
| A46929 | 33871024 | Clin Sci (Lond) | Arrb2 causes hepatic lipid metabolism disorder via AMPK pathway based on metabolomics in alcoholic fatty liver. | 2021 | Details |
| A46930 | 33860120 | Hepatol Commun | Clinical Presentation and Gene Expression of Acute Alcohol-Induced Microvesicular Steatosis Mimicking Alcoholic Hepatitis. | 2021 | Details |
| A46931 | 33816353 | Front Cell Infect Microbiol | Streptococcus, the Predominant Bacterium to Predict the Severity of Liver Injury in Alcoholic Liver Disease. | 2021 | Details |
| A46933 | 33713857 | Biochem Biophys Res Commun | Mesencephalic astrocyte-derived neurotrophic factor alleviates alcohol induced hepatic steatosis via activating Stat3-mediated autophagy. | 2021 | Details |
| A46934 | 33676386 | Physiol Res | Downregulation of long non-coding RNA AIRN promotes mitophagy in alcoholic fatty hepatocytes by promoting ubiquitination of mTOR. | 2021 | Details |
| A46935 | 33672832 | Biomolecules | Serum Acylcarnitines Associated with High Short-Term Mortality in Patients with Alcoholic Hepatitis. | 2021 | Details |
| A46936 | 33598648 | JHEP Rep | Gut dysbiosis as a driver in alcohol-induced liver injury. | 2020 | Details |
| A46937 | 33520734 | Front Cell Infect Microbiol | Prognostic Significance of End-Stage Liver Diseases, Respiratory Tract Infection, and Chronic Kidney Diseases in Symptomatic Acute Hepatitis E. | 2021 | Details |
| A46938 | 33485268 | Biochem Biophys Res Commun | Nuclear factor Y participates in alcoholic liver disease by activating SREBP1 expression in mice. | 2021 | Details |
| A46939 | 33481293 | FASEB J | Beneficial effects of an endogenous enrichment in n3-PUFAs on Wnt signaling are associated with attenuation of alcohol-mediated liver disease in mice. | 2021 | Details |
| A46940 | 33443222 | Proc Natl Acad Sci U S A | Oral administration of PEGylated TLR7 ligand ameliorates alcohol-associated liver disease via the induction of IL-22. | 2020 | Details |
| A46941 | 33352397 | Cytokine | IL-8 exacerbates alcohol-induced fatty liver disease via the Akt/HIF-1α pathway in human IL-8-expressing mice. | 2020 | Details |
| A46942 | 33340581 | J Hepatol | NNMT aggravates hepatic steatosis, but alleviates liver injury in alcoholic liver disease. | 2020 | Details |
| A46943 | 33249138 | Free Radic Biol Med | The critical role of redox regulation of PTEN and peroxiredoxin III in alcoholic fatty liver. | 2020 | Details |
| A46944 | 33177163 | Gut | ATF4 activation promotes hepatic mitochondrial dysfunction by repressing NRF1-TFAM signalling in alcoholic steatohepatitis. | 2020 | Details |
| A46945 | 33162823 | Int J Biol Sci | Emerging Roles of SIRT1 in Alcoholic Liver Disease. | 2020 | Details |
| A46946 | 33132639 | World J Gastroenterol | Longitudinal decrease in platelet counts as a surrogate marker of liver fibrosis. | 2020 | Details |
| A46947 | 33067186 | Dis Model Mech | Alcoholic hepatitis and metabolic disturbance in female mice: a more tractable model than Nrf2 -/- animals. | 2020 | Details |
| A46949 | 32960884 | PLoS Comput Biol | Alcoholic liver disease: A registry view on comorbidities and disease prediction. | 2020 | Details |
| A46950 | 32935794 | Rev Assoc Med Bras (1992) | Comparison of tru-cut biopsy and fine-needle aspiration cytology in an experimental alcoholic liver disease model. | 2020 | Details |
| A46951 | 32879433 | Commun Biol | Oxidation of fish oil exacerbates alcoholic liver disease by enhancing intestinal dysbiosis in mice. | 2020 | Details |
| A46952 | 32790342 | ACS Nano | Luminescence Imaging of Acute Liver Injury by Biodegradable and Biocompatible Nanoprobes. | 2020 | Details |
| A46953 | 32749590 | Eur Radiol | Coronary atherosclerosis profile in patients with end-stage liver disease prior to liver transplantation due to alcoholic fatty liver: a coronary CTA study. | 2020 | Details |
| A46956 | 32583604 | Mol Nutr Food Res | Microbial Products and Metabolites Contributing to Alcohol-Related Liver Disease. | 2020 | Details |
| A46957 | 32544093 | JCI Insight | Chronic-plus-binge alcohol intake induces production of proinflammatory mtDNA-enriched extracellular vesicles and steatohepatitis via ASK1/p38MAPKα-dependent mechanisms. | 2020 | Details |
| A46958 | 32418220 | Hepatology | Inhibition of Sphingosine-1-Phosphate-Induced Th17 Cells Ameliorates Alcohol-Associated Steatohepatitis in Mice. | 2021 | Details |
| A46959 | 32404932 | Lab Invest | Enhanced alcoholic liver disease in mice with intestine-specific farnesoid X receptor deficiency. | 2020 | Details |
| A46960 | 32306456 | Liver Int | Dimethyl fumarate ameliorates hepatic inflammation in alcohol related liver disease. | 2020 | Details |
| A46961 | 32282858 | PLoS Genet | A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease. | 2020 | Details |
| A46962 | 32267550 | Alcohol Clin Exp Res | Dihydromyricetin Protects the Liver via Changes in Lipid Metabolism and Enhanced Ethanol Metabolism. | 2020 | Details |
| A46963 | 32206109 | Theranostics | NIK links inflammation to hepatic steatosis by suppressing PPARα in alcoholic liver disease. | 2020 | Details |
| A46964 | 32129352 | Food Funct | Rosmarinic acid alleviates ethanol-induced lipid accumulation by repressing fatty acid biosynthesis. | 2020 | Details |
| A46966 | 32087348 | J Hepatol | Hepatic stellate cell activation promotes alcohol-induced steatohepatitis through Igfbp3 and SerpinA12. | 2020 | Details |
| A46967 | 32045450 | PLoS One | Mesenchymal stem cells reduce alcoholic hepatitis in mice via suppression of hepatic neutrophil and macrophage infiltration, and of oxidative stress. | 2020 | Details |
| A46968 | 32045262 | Am J Physiol Endocrinol Metab | Neuronal modulation of hepatic lipid accumulation induced by bingelike drinking. | 2020 | Details |
| A46969 | 31955762 | Food Res Int | Alteration of gut microbiota composition by short-term low-dose alcohol intake is restored by fermented rice liquor in mice. | 2019 | Details |
| A46970 | 31954208 | J Hepatol | Long-term outcomes in patients with decompensated alcohol-related liver disease, steatohepatitis and Maddrey's discriminant function <32. | 2020 | Details |
| A46971 | 31930010 | Hepatobiliary Surg Nutr | Prof. Carlos J. Pirola: the putative therapeutics of alcoholic fatty liver disease (AFLD) and non-AFLD (NAFLD): a systems biology approach. | 2019 | Details |
| A46972 | 31711913 | Ann Hepatol | Calling a stage-based treatment model for chronic liver diseases in China mainland. | 2019 | Details |
| A46975 | 31612718 | J Proteome Res | Proteomic Investigations of Transcription Factors Critical in Geniposide-Mediated Suppression of Alcoholic Steatosis and in Overdose-Induced Hepatotoxicity on Liver in Rats. | 2019 | Details |
| A46976 | 31586017 | J Lipid Res | Decreased ω-6:ω-3 PUFA ratio attenuates ethanol-induced alterations in intestinal homeostasis, microbiota, and liver injury. | 2019 | Details |
| A46977 | 31493100 | Wien Klin Wochenschr | Patterns and prevalence of dyslipidemia in patients with different etiologies of chronic liver disease. | 2019 | Details |
| A46978 | 31491888 | Biomedicines | Alcoholic Liver Disease: Current Mechanistic Aspects with Focus on Their Clinical Relevance. | 2019 | Details |
| A46979 | 31479733 | Biochim Biophys Acta Mol Cell Biol Lipids | Estrogen-related receptor γ controls sterol regulatory element-binding protein-1c expression and alcoholic fatty liver. | 2019 | Details |
| A46980 | 31463983 | Lipids | Vitamin D Deficiency Attenuates Acute Alcohol-Induced Hepatic Lipid Accumulation in Mice. | 2019 | Details |
| A46981 | 31438968 | Cell Commun Signal | Parkin deficiency prevents chronic ethanol-induced hepatic lipid accumulation through β-catenin accumulation. | 2019 | Details |
| A46982 | 31336037 | Mol Nutr Food Res | The Preventative Effects of Procyanidin on Binge Ethanol-Induced Lipid Accumulation and ROS Overproduction via the Promotion of Hepatic Autophagy. | 2019 | Details |
| A46983 | 31321478 | J Mol Med (Berl) | S100A4 promotes inflammation but suppresses lipid accumulation via the STAT3 pathway in chronic ethanol-induced fatty liver. | 2019 | Details |
| A46984 | 31295533 | J Hepatol | The epigenetic regulator SIRT6 protects the liver from alcohol-induced tissue injury by reducing oxidative stress in mice. | 2019 | Details |
| A46985 | 31265202 | IUBMB Life | Dihydroartemisinin attenuates alcoholic fatty liver through regulation of lipin-1 signaling. | 2019 | Details |
| A46986 | 31241423 | J Am Coll Nutr | Hepatoprotective Effect of Probiotic Lactobacillus rhamnosus GG Through the Modulation of Gut Permeability and Inflammasomes in a Model of Alcoholic Liver Disease in Zebrafish. | 2019 | Details |
| A46987 | 31188604 | J Proteome Res | Profiling of Polar Metabolites in Mouse Feces Using Four Analytical Platforms to Study the Effects Of Cathelicidin-Related Antimicrobial Peptide in Alcoholic Liver Disease. | 2019 | Details |
| A46988 | 31173814 | J Hepatol | Natural history of histologically proven alcohol-related liver disease: A systematic review. | 2019 | Details |
| A46989 | 31168926 | Mol Nutr Food Res | Myricetin Ameliorates Ethanol-Induced Lipid Accumulation in Liver Cells by Reducing Fatty Acid Biosynthesis. | 2019 | Details |
| A46991 | 31076642 | Cell Res | Complement C3 activation regulates the production of tRNA-derived fragments Gly-tRFs and promotes alcohol-induced liver injury and steatosis. | 2019 | Details |
| A46992 | 31063562 | JAMA | Prevalence of Alcoholic Fatty Liver Disease Among Adults in the United States, 2001-2016. | 2019 | Details |
| A46993 | 31034614 | Alcohol Clin Exp Res | AIN-93 Diet as an Alternative Model to Lieber-DeCarli Diet for Alcoholic Cardiomyopathy. | 2019 | Details |
| A46994 | 30938072 | Mol Nutr Food Res | Wolfberry-Derived Zeaxanthin Dipalmitate Attenuates Ethanol-Induced Hepatic Damage. | 2019 | Details |
| A46995 | 30935969 | Metabolism | Chitinase-3-like-1 deficiency attenuates ethanol-induced liver injury by inhibition of sterol regulatory element binding protein 1-dependent triglyceride synthesis. | 2019 | Details |
| A46996 | 30857422 | FASEB J | Solid-state fermented Chinese alcoholic beverage (baijiu) and ethanol resulted in distinct metabolic and microbiome responses. | 2019 | Details |
| A46997 | 30803859 | Dig Liver Dis | FXR deficiency alters bile acid pool composition and exacerbates chronic alcohol induced liver injury. | 2019 | Details |
| A46998 | 30802717 | Redox Biol | Systemic inactivation of hypoxia-inducible factor prolyl 4-hydroxylase 2 in mice protects from alcohol-induced fatty liver disease. | 2019 | Details |
| A46999 | 30773529 | Med Sci Monit | Evaluation of Relationship between Occurrence of Liver Cancer and Methylation of Fragile Histidine Triad (FHIT) and P16 Genes. | 2019 | Details |
| A47001 | 30721374 | Cell Biol Toxicol | Activation of SIRT1 by L-serine increases fatty acid oxidation and reverses insulin resistance in C2C12 myotubes. | 2019 | Details |
| A47002 | 30660600 | Alcohol | Usefulness of adult medaka fish as a model for the evaluation of alcoholic fatty liver. | 2019 | Details |
| A47003 | 30658728 | J Hepatol | Non-invasive diagnosis and biomarkers in alcohol-related liver disease. | 2019 | Details |
| A47004 | 30643227 | Nat Rev Gastroenterol Hepatol | Alcohol, liver disease and the gut microbiota. | 2019 | Details |
| A47005 | 30403751 | PLoS One | The sex specific effect of alcohol consumption on circulating levels of CTRP3. | 2018 | Details |
| A47006 | 30256818 | PLoS One | Ethanol and unsaturated dietary fat induce unique patterns of hepatic ω-6 and ω-3 PUFA oxylipins in a mouse model of alcoholic liver disease. | 2018 | Details |
| A47007 | 30248395 | Alcohol | Pharmacokinetic changes of tramadol in rats with hepatotoxicity induced by ethanol and acetaminophen in perfused rat liver model. | 2018 | Details |
| A47008 | 30192394 | Alcohol Clin Exp Res | Dietary Macronutrient Composition Determines the Contribution of DGAT1 to Alcoholic Steatosis. | 2018 | Details |
| A47009 | 30179264 | Hepatology | Pharmacological Inhibition of CCR2/5 Signaling Prevents and Reverses Alcohol-Induced Liver Damage, Steatosis, and Inflammation in Mice. | 2019 | Details |
| A47010 | 30150688 | Sci Rep | Ethanol and C2 ceramide activate fatty acid oxidation in human hepatoma cells. | 2018 | Details |
| A47011 | 30115921 | Nat Rev Dis Primers | Alcoholic liver disease. | 2018 | Details |
| A47012 | 30105955 | Exp Biol Med (Maywood) | Mulberry and dandelion water extracts prevent alcohol-induced steatosis with alleviating gut microbiome dysbiosis. | 2018 | Details |
| A47013 | 30071471 | Redox Biol | Pomegranate prevents binge alcohol-induced gut leakiness and hepatic inflammation by suppressing oxidative and nitrative stress. | 2018 | Details |
| A47014 | 30048873 | Drug Alcohol Depend | Ultrasound findings of liver damage in a series of patients consecutively admitted for treatment of alcohol use disorder. | 2018 | Details |
| A47015 | 29884546 | Mol Metab | Hepatocyte toll-like receptor 4 deficiency protects against alcohol-induced fatty liver disease. | 2018 | Details |
| A47016 | 29852391 | Biomed Pharmacother | Increased hepatic FAT/CD36, PTP1B and decreased HNF4A expression contributes to dyslipidemia associated with ethanol-induced liver dysfunction: Rescue effect of ginger extract. | 2018 | Details |
| A47017 | 29763374 | Am J Physiol Endocrinol Metab | Transgenic overexpression of CTRP3 prevents alcohol-induced hepatic triglyceride accumulation. | 2018 | Details |
| A47018 | 29708448 | Expert Opin Pharmacother | Alcoholic steatohepatitis (ASH) and alcoholic hepatitis (AH): cascade of events, clinical aspects, and pharmacotherapy options. | 2018 | Details |
| A47019 | 29457836 | Hepatology | DEP domain-containing mTOR-interacting protein suppresses lipogenesis and ameliorates hepatic steatosis and acute-on-chronic liver injury in alcoholic liver disease. | 2018 | Details |
| A47020 | 29452206 | J Hepatol | SNX10 mediates alcohol-induced liver injury and steatosis by regulating the activation of chaperone-mediated autophagy. | 2018 | Details |
| A47021 | 29368944 | Am J Physiol Gastrointest Liver Physiol | A specific amino acid formula prevents alcoholic liver disease in rodents. | 2018 | Details |
| A47022 | 29352167 | Sci Rep | SREBP1c mediates the effect of acetaldehyde on Cidea expression in Alcoholic fatty liver Mice. | 2018 | Details |
| A47023 | 29351393 | Am J Physiol Gastrointest Liver Physiol | Liver tissue metabolically transformed by alcohol induces immune recognition of liver self-proteins but not in vivo inflammation. | 2017 | Details |
| A47024 | 29343427 | J Hepatol | Controlled attenuation parameter and alcoholic hepatic steatosis: Diagnostic accuracy and role of alcohol detoxification. | 2018 | Details |
| A47025 | 29337245 | Exp Mol Pathol | Hepatic alcohol dehydrogenase deficiency induces pancreatic injury in chronic ethanol feeding model of deer mice. | 2018 | Details |
| A47026 | 29336434 | Am J Gastroenterol | ACG Clinical Guideline: Alcoholic Liver Disease. | 2018 | Details |
| A47027 | 29317476 | J Pharmacol Exp Ther | Poly(ADP-Ribose) Polymerase Inhibitor PJ34 Attenuated Hepatic Triglyceride Accumulation in Alcoholic Fatty Liver Disease in Mice. | 2018 | Details |
| A47028 | 29133292 | J Lipid Res | Intracellular hepatitis B virus increases hepatic cholesterol deposition in alcoholic fatty liver via hepatitis B core protein. | 2017 | Details |
| A47029 | 29095436 | Cell Death Dis | RNA-sequencing-based comparative analysis of human hepatic progenitor cells and their niche from alcoholic steatohepatitis livers. | 2017 | Details |
| A47030 | 28941686 | Food Res Int | Barley sprout extracts reduce hepatic lipid accumulation in ethanol-fed mice by activating hepatic AMP-activated protein kinase. | 2017 | Details |
| A47031 | 28882574 | Toxicology | Kupffer cells activation promoted binge drinking-induced fatty liver by activating lipolysis in white adipose tissues. | 2017 | Details |
| A47032 | 28864659 | FASEB J | A novel role for ceramide synthase 6 in mouse and human alcoholic steatosis. | 2017 | Details |
| A47033 | 28847514 | Biochim Biophys Acta Mol Basis Dis | Omega-3 polyunsaturated fatty acids ameliorate ethanol-induced adipose hyperlipolysis: A mechanism for hepatoprotective effect against alcoholic liver disease. | 2017 | Details |