Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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40433 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A47035 | 28689299 | J Mol Med (Berl) | 4-O'-methylhonokiol protects from alcohol/carbon tetrachloride-induced liver injury in mice. | 2017 | Details |
| A47036 | 28667706 | Pathol Int | An autopsy case of non-traumatic fat embolism syndrome. | 2017 | Details |
| A47037 | 28536109 | J Lipid Res | Effect of iron on cholesterol 7α-hydroxylase expression in alcohol-induced hepatic steatosis in mice. | 2017 | Details |
| A47038 | 28500689 | IUBMB Life | Blockade of hedgehog pathway is required for the protective effects of magnesium isoglycyrrhizinate against ethanol-induced hepatocyte steatosis and apoptosis. | 2017 | Details |
| A47039 | 28492308 | Anal Chem | Visualizing the Conversion Process of Alcohol-Induced Fatty Liver to Steatohepatitis in Vivo with a Fluorescent Nanoprobe. | 2017 | Details |
| A47040 | 28476407 | Toxicol Appl Pharmacol | Curcumin improves alcoholic fatty liver by inhibiting fatty acid biosynthesis. | 2017 | Details |
| A47041 | 28467182 | Exp Biol Med (Maywood) | Roles of silent information regulator 1-serine/arginine-rich splicing factor 10-lipin 1 axis in the pathogenesis of alcohol fatty liver disease. | 2017 | Details |
| A47042 | 28424943 | Dig Dis Sci | Intestinal Alkaline Phosphatase Attenuates Alcohol-Induced Hepatosteatosis in Mice. | 2017 | Details |
| A47043 | 28274894 | J Ethnopharmacol | Effects of antrosterol from Antrodia camphorata submerged whole broth on lipid homeostasis, antioxidation, alcohol clearance, and anti-inflammation in livers of chronic-alcohol fed mice. | 2017 | Details |
| A47044 | 28228158 | Lipids Health Dis | Flaxseed oil ameliorates alcoholic liver disease via anti-inflammation and modulating gut microbiota in mice. | 2017 | Details |
| A47045 | 28134813 | Biomolecules | Key Events Participating in the Pathogenesis of  Alcoholic Liver Disease. | 2017 | Details |
| A47046 | 28112200 | Sci Rep | Reduction of hepatic fibrosis by overexpression of von Hippel-Lindau protein in experimental models of chronic liver disease. | 2017 | Details |
| A47047 | 28042659 | Alcohol Clin Exp Res | Does Genetic Loss of Immunoglobulin A Have No Impact on Alcoholic Liver Disease? | 2016 | Details |
| A47048 | 27940551 | J Investig Med | Management of alcohol misuse in patients with liver diseases. | 2016 | Details |
| A47049 | 27871879 | J Hepatol | Aging aggravates alcoholic liver injury and fibrosis in mice by downregulating sirtuin 1 expression. | 2016 | Details |
| A47050 | 27861855 | Int J Cancer | Effect of statin on hepatocellular carcinoma in patients with type 2 diabetes: A nationwide nested case-control study. | 2016 | Details |
| A47051 | 27837167 | Toxicol Sci | Nrf2 Activation Is Required for Ligustrazine to Inhibit Hepatic Steatosis in Alcohol-Preferring Mice and Hepatocytes. | 2016 | Details |
| A47052 | 27824131 | Sci Rep | Infliximab and Dexamethasone Attenuate the Ductular Reaction in Mice. | 2016 | Details |
| A47053 | 27821289 | J Nutr Biochem | Evaluating the effects of refined carbohydrate and fat diets with acute ethanol consumption using a mouse model of alcoholic liver injury. | 2016 | Details |
| A47055 | 27746183 | Am J Pathol | Inhibition of Poly(ADP-Ribose) Polymerase-1 Protects Chronic Alcoholic Liver Injury. | 2016 | Details |
| A47056 | 27679493 | Gut | MicroRNA-223 ameliorates alcoholic liver injury by inhibiting the IL-6-p47phox-oxidative stress pathway in neutrophils. | 2016 | Details |
| A47057 | 27666676 | Sci Rep | Myeloid Cell-Specific Lipin-1 Deficiency Stimulates Endocrine Adiponectin-FGF15 Axis and Ameliorates Ethanol-Induced Liver Injury in Mice. | 2016 | Details |
| A47058 | 27630043 | Nat Commun | MBOAT7 rs641738 increases risk of liver inflammation and transition to fibrosis in chronic hepatitis C. | 2016 | Details |
| A47059 | 27455313 | Nutrients | Barley Sprouts Extract Attenuates Alcoholic Fatty Liver Injury in Mice by Reducing Inflammatory Response. | 2016 | Details |
| A47061 | 27404390 | Sci Rep | Suppression of PPARγ-mediated monoacylglycerol O-acyltransferase 1 expression ameliorates alcoholic hepatic steatosis. | 2016 | Details |
| A47062 | 27346657 | Sci Rep | The Cannabinoid Receptor 2 Protects Against Alcoholic Liver Disease Via a Macrophage Autophagy-Dependent Pathway. | 2016 | Details |
| A47063 | 27342423 | J Investig Med | Alcohol and fat promote steatohepatitis: a critical role for fat-specific protein 27/CIDEC. | 2016 | Details |
| A47064 | 27236145 | Ann Hepatol |  Alcoholic hepatitis: How far are we and where are we going? | 2017 | Details |
| A47065 | 27220557 | Sci Rep | Dietary α-linolenic acid-rich flaxseed oil prevents against alcoholic hepatic steatosis via ameliorating lipid homeostasis at adipose tissue-liver axis in mice. | 2016 | Details |
| A47066 | 27080262 | Br J Nutr | Decreased hepatic iron in response to alcohol may contribute to alcohol-induced suppression of hepcidin. | 2016 | Details |
| A47067 | 27044810 | Biomed Pharmacother | Diallyl trisulfide attenuates ethanol-induced hepatic steatosis by inhibiting oxidative stress and apoptosis. | 2016 | Details |
| A47068 | 26968209 | Am J Physiol Gastrointest Liver Physiol | Enhanced ethanol catabolism in orphan nuclear receptor SHP-null mice. | 2016 | Details |
| A47069 | 26934429 | Cochrane Database Syst Rev | Ultrasonography for diagnosis of alcoholic cirrhosis in people with alcoholic liver disease. | 2016 | Details |
| A47071 | 26867181 | Cell Host Microbe | Intestinal REG3 Lectins Protect against Alcoholic Steatohepatitis by Reducing Mucosa-Associated Microbiota and Preventing Bacterial Translocation. | 2016 | Details |
| A47072 | 26858343 | Gut | Reversal of murine alcoholic steatohepatitis by pepducin-based functional blockade of interleukin-8 receptors. | 2016 | Details |
| A47073 | 26854922 | Food Chem Toxicol | Ethanol and fatty acids impair lipid homeostasis in an in vitro model of hepatic steatosis. | 2016 | Details |
| A47074 | 26835538 | Am J Pathol | Murine Models of Acute Alcoholic Hepatitis and Their Relevance to Human Disease. | 2016 | Details |
| A47075 | 26801973 | BMC Complement Altern Med | Hepatoprotective effect of licorice, the root of Glycyrrhiza uralensis Fischer, in alcohol-induced fatty liver disease. | 2016 | Details |
| A47076 | 26751488 | Biomolecules | Alcoholic Liver Disease: Update on the Role of Dietary Fat. | 2016 | Details |
| A47077 | 26637972 | Biofactors | Endogenously elevated n-3 polyunsaturated fatty acids alleviate acute ethanol-induced liver steatosis. | 2015 | Details |
| A47078 | 26626356 | J Microbiol | Lactobacillus rhamnosus CCFM1107 treatment ameliorates alcohol-induced liver injury in a mouse model of chronic alcohol feeding. | 2015 | Details |
| A47079 | 26617183 | Toxicol Lett | Lactobacillus rhamnosus GG supernatant promotes intestinal barrier function, balances Treg and TH17 cells and ameliorates hepatic injury in a mouse model of chronic-binge alcohol feeding. | 2015 | Details |
| A47080 | 26610588 | Biomolecules | High Intrinsic Aerobic Capacity Protects against Ethanol-Induced Hepatic Injury and Metabolic Dysfunction: Study Using High Capacity Runner Rat Model. | 2015 | Details |
| A47081 | 26576483 | J Hepatol | Enhanced expression of c-myc in hepatocytes promotes initiation and progression of alcoholic liver disease. | 2015 | Details |
| A47082 | 26564773 | Alcohol Alcohol | Melatonin Upregulates the Activity of AMPK and Attenuates Lipid Accumulation in Alcohol-induced Rats. | 2015 | Details |
| A47083 | 26556636 | Alcohol Clin Exp Res | Microbiota Protects Mice Against Acute Alcohol-Induced Liver Injury. | 2015 | Details |
| A47084 | 26511776 | Alcohol Alcohol | The Role of Ceramide in the Pathogenesis of Alcoholic Liver Disease. | 2015 | Details |
| A47085 | 26497211 | Oncotarget | Identification of cytochrome CYP2E1 as critical mediator of synergistic effects of alcohol and cellular lipid accumulation in hepatocytes in vitro. | 2015 | Details |
| A47086 | 26494961 | World J Gastroenterol | Non-invasive assessment of liver fibrosis in patients with alcoholic liver disease. | 2015 | Details |
| A47087 | 26493454 | BMC Syst Biol | Systems analysis of non-parenchymal cell modulation of liver repair across multiple regeneration modes. | 2015 | Details |
| A47088 | 26459052 | Int Immunopharmacol | Ligustrazine prevents alcohol-induced liver injury by attenuating hepatic steatosis and oxidative stress. | 2015 | Details |
| A47089 | 26436364 | Ann Hepatol | Maternal separation on the ethanol-preferring adult rat liver structure. | 2016 | Details |
| A47090 | 26345299 | J Agric Food Chem | Gynura procumbens Reverses Acute and Chronic Ethanol-Induced Liver Steatosis through MAPK/SREBP-1c-Dependent and -Independent Pathways. | 2015 | Details |
| A47091 | 26305715 | IUBMB Life | Curcumin attenuates ethanol-induced hepatic steatosis through modulating Nrf2/FXR signaling in hepatocytes. | 2015 | Details |
| A47092 | 26266409 | Int J Mol Sci | Changes of the Cytoplasmic Proteome in Response to Alcoholic Hepatotoxicity in Rats. | 2015 | Details |
| A47093 | 26099526 | Gastroenterology | Fat-Specific Protein 27/CIDEC Promotes Development of Alcoholic Steatohepatitis in Mice and Humans. | 2015 | Details |
| A47094 | 26092866 | J Lipid Res | FGF21 mediates alcohol-induced adipose tissue lipolysis by activation of systemic release of catecholamine in mice. | 2015 | Details |
| A47095 | 26033752 | Hepatology | Short- or long-term high-fat diet feeding plus acute ethanol binge synergistically induce acute liver injury in mice: an important role for CXCL1. | 2015 | Details |
| A47096 | 26030870 | PLoS One | Establishment of the tree shrew as an alcohol-induced Fatty liver model for the study of alcoholic liver diseases. | 2015 | Details |
| A47097 | 26025474 | Biochimie | Excessive bile acid activated NF-kappa B and promoted the development of alcoholic steatohepatitis in farnesoid X receptor deficient mice. | 2015 | Details |
| A47098 | 26022806 | J Lipid Res | Ethanol-induced hepatic steatosis is modulated by glycogen level in the liver. | 2015 | Details |
| A47099 | 25960184 | Alcohol | Dissociation between diurnal cycles in locomotor activity, feeding behavior and hepatic PERIOD2 expression in chronic alcohol-fed mice. | 2015 | Details |
| A47100 | 25923904 | Zebrafish | Development of an Animal Model for Alcoholic Liver Disease in Zebrafish. | 2015 | Details |
| A47106 | 25892964 | Int J Biol Sci | The effects of insulin pre-administration in mice exposed to ethanol: alleviating hepatic oxidative injury through anti-oxidative, anti-apoptotic activities and deteriorating hepatic steatosis through SRBEP-1c activation. | 2015 | Details |
| A47107 | 25879823 | BMC Fam Pract | Primary health care utilization for alcohol-attributed diseases in British Columbia Canada 2001-2011. | 2015 | Details |
| A47108 | 25872593 | Alcohol Clin Exp Res | Alcoholic liver disease: the gut microbiome and liver cross talk. | 2015 | Details |
| A47109 | 25869468 | J Hepatobiliary Pancreat Sci | Recent advancement of molecular mechanisms of liver fibrosis. | 2015 | Details |
| A47110 | 25833546 | Adv Exp Med Biol | Taurine accelerates alcohol and fat metabolism of rats with alcoholic Fatty liver disease. | 2015 | Details |
| A47111 | 25801055 | Int J Biochem Cell Biol | Decoding liver injury: A regulatory role for histone modifications. | 2015 | Details |
| A47112 | 25789959 | Medicine (Baltimore) | Changes in tumor necrosis factor-α, heat shock protein 70, malondialdehyde, and superoxide dismutase in patients with different severities of alcoholic fatty liver disease: a prospective observational study. | 2015 | Details |
| A47113 | 25773117 | Clin Chim Acta | MicroRNA responses to environmental liver carcinogens: Biological and clinical significance. | 2015 | Details |
| A47114 | 25717264 | World J Gastroenterol | Autoimmune hepatitis-primary biliary cirrhosis concurrent with biliary stricture after liver transplantation. | 2015 | Details |
| A47115 | 25703252 | Alcohol Clin Exp Res | The adiponectin-SIRT1-AMPK pathway in alcoholic fatty liver disease in the rat. | 2015 | Details |
| A47116 | 25702770 | Alcohol Clin Exp Res | Ethnic differences in presentation and severity of alcoholic liver disease. | 2015 | Details |
| A47117 | 25644346 | J Nutr | L-serine supplementation attenuates alcoholic fatty liver by enhancing homocysteine metabolism in mice and rats. | 2014 | Details |
| A47118 | 25622859 | J Nutr Biochem | Enhanced AMPK phosphorylation contributes to the beneficial effects of Lactobacillus rhamnosus GG supernatant on chronic-alcohol-induced fatty liver disease. | 2014 | Details |
| A47119 | 25595739 | Alcohol Alcohol | The role of lipin-1 in the pathogenesis of alcoholic fatty liver. | 2015 | Details |
| A47120 | 25592162 | Arch Biochem Biophys | Dietary tomato powder inhibits alcohol-induced hepatic injury by suppressing cytochrome p450 2E1 induction in rodent models. | 2015 | Details |
| A47121 | 25582105 | J Hepatol | Invariant NKT cells promote alcohol-induced steatohepatitis through interleukin-1β in mice. | 2015 | Details |
| A47122 | 25561792 | World J Gastroenterol | Delayed ethanol elimination and enhanced susceptibility to ethanol-induced hepatosteatosis after liver resection. | 2014 | Details |
| A47123 | 25559494 | Alcohol | The effect of acute alcohol intoxication on gut wall integrity in healthy male volunteers; a randomized controlled trial. | 2014 | Details |
| A47124 | 25557254 | J Pathol | 22-S-Hydroxycholesterol protects against ethanol-induced liver injury by blocking the auto/paracrine activation of MCP-1 mediated by LXRα. | 2015 | Details |
| A47125 | 25543082 | J Hepatol | Pharmacological activation of aldehyde dehydrogenase 2 by Alda-1 reverses alcohol-induced hepatic steatosis and cell death in mice. | 2014 | Details |
| A47126 | 25494594 | Lipids Health Dis | Protective effect of corn peptides against alcoholic liver injury in men with chronic alcohol consumption: a randomized double-blind placebo-controlled study. | 2014 | Details |
| A47127 | 25462064 | Redox Biol | Intestinal CYP2E1: A mediator of alcohol-induced gut leakiness. | 2014 | Details |
| A47128 | 25462060 | Redox Biol | Regulation of the effects of CYP2E1-induced oxidative stress by JNK signaling. | 2014 | Details |
| A47129 | 25455889 | Food Chem Toxicol | Berberine protects liver from ethanol-induced oxidative stress and steatosis in mice. | 2014 | Details |
| A47130 | 25449367 | Alcohol | Increasing serum pre-adipocyte factor-1 (Pref-1) correlates with decreased body fat, increased free fatty acids, and level of recent alcohol consumption in excessive alcohol drinkers. | 2014 | Details |
| A47131 | 25409421 | J Phys Chem B | Kinetics and thermodynamics of 1-hydroxyethyl radical reaction with unsaturated lipids and prenylflavonoids. | 2014 | Details |
| A47132 | 25400459 | World J Gastroenterol | Metformin does not improve survival in patients with hepatocellular carcinoma. | 2014 | Details |
| A47133 | 25399514 | J Thromb Haemost | Protein S exacerbates alcoholic hepatitis by stimulating liver natural killer T cells. | 2014 | Details |
| A47134 | 25362106 | J Pharmacol Exp Ther | Demethyleneberberine, a natural mitochondria-targeted antioxidant, inhibits mitochondrial dysfunction, oxidative stress, and steatosis in alcoholic liver disease mouse model. | 2014 | Details |
| A47135 | 25355486 | Acta Biochim Biophys Sin (Shanghai) | FGF21 treatment ameliorates alcoholic fatty liver through activation of AMPK-SIRT1 pathway. | 2014 | Details |
| A47136 | 25278703 | World J Gastroenterol | Osteopontin is an important mediator of alcoholic liver disease via hepatic stellate cell activation. | 2014 | Details |
| A47137 | 25278689 | World J Gastroenterol | Alcoholic liver disease: treatment. | 2014 | Details |
| A47138 | 25278688 | World J Gastroenterol | New advances in molecular mechanisms and emerging therapeutic targets in alcoholic liver diseases. | 2014 | Details |
| A47139 | 25228362 | Pharmacology | Emodin ameliorates ethanol-induced fatty liver injury in mice. | 2014 | Details |
| A47140 | 25132354 | Hepatology | Osteopontin deficiency does not prevent but promotes alcoholic neutrophilic hepatitis in mice. | 2014 | Details |
| A47141 | 25107314 | Drug Alcohol Depend | Altered oxidative stress/antioxidant status in blood of alcoholic subjects is associated with alcoholic liver disease. | 2014 | Details |
| A47142 | 25104501 | Am J Physiol Gastrointest Liver Physiol | An alteration of the gut-liver axis drives pulmonary inflammation after intoxication and burn injury in mice. | 2014 | Details |