Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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40433 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A47143 | 25024695 | Front Pharmacol | Glutathione and mitochondria. | 2014 | Details |
| A47144 | 25017766 | Mol Med Rep | Pattern of microRNA expression associated with different stages of alcoholic liver disease in rat models. | 2014 | Details |
| A47145 | 24950483 | J Hepatol | How predictive quantitative modelling of tissue organisation can inform liver disease pathogenesis. | 2014 | Details |
| A47146 | 24930470 | Alcohol Clin Exp Res | Pyrroloquinoline quinone-secreting probiotic Escherichia coli Nissle 1917 ameliorates ethanol-induced oxidative damage and hyperlipidemia in rats. | 2014 | Details |
| A47147 | 24859453 | J Hepatol | Inhibition of heat shock protein 90 alleviates steatosis and macrophage activation in murine alcoholic liver injury. | 2014 | Details |
| A47148 | 24835349 | Kaohsiung J Med Sci | Interleukin 10 promoter haplotype is associated with alcoholic liver cirrhosis in Taiwanese patients. | 2014 | Details |
| A47149 | 24833709 | Am J Physiol Gastrointest Liver Physiol | The inhibitory effect of ethanol on Sestrin3 in the pathogenesis of ethanol-induced liver injury. | 2014 | Details |
| A47150 | 24831094 | PLoS One | Absence of perilipin 2 prevents hepatic steatosis, glucose intolerance and ceramide accumulation in alcohol-fed mice. | 2014 | Details |
| A47151 | 24828027 | J Nutr | Luteolin alleviates alcoholic liver disease induced by chronic and binge ethanol feeding in mice. | 2014 | Details |
| A47152 | 24815155 | Transplant Proc | Γ-glutamyl transferase as an early and sensitive marker in ethanol-induced liver injury of rats. | 2014 | Details |
| A47154 | 24797033 | Alcohol Clin Exp Res | Involvement of insulin resistance in the protective effect of metformin against alcoholic liver injury. | 2014 | Details |
| A47155 | 24793348 | J Clin Lipidol | Association between alcohol intake, overweight, and serum lipid levels and the risk analysis associated with the development of dyslipidemia. | 2014 | Details |
| A47156 | 24746831 | J Nutr Biochem | Quercetin prevents ethanol-induced iron overload by regulating hepcidin through the BMP6/SMAD4 signaling pathway. | 2014 | Details |
| A47157 | 24740309 | PLoS One | Zeaxanthin dipalmitate therapeutically improves hepatic functions in an alcoholic fatty liver disease model through modulating MAPK pathway. | 2014 | Details |
| A47158 | 24730561 | Alcohol Clin Exp Res | Methylation and gene expression responses to ethanol feeding and betaine supplementation in the cystathionine beta synthase-deficient mouse. | 2014 | Details |
| A47159 | 24722988 | J Biol Chem | Identification of 5' AMP-activated kinase as a target of reactive aldehydes during chronic ingestion of high concentrations of ethanol. | 2014 | Details |
| A47160 | 24713392 | Am J Pathol | M2 kupffer cells promote hepatocyte senescence: an IL-6-dependent protective mechanism against alcoholic liver disease. | 2014 | Details |
| A47161 | 24656653 | Gastroenterol Hepatol | Alcoholic hepatitis: Prognosis and treatment. | 2014 | Details |
| A47162 | 24633014 | Cell Mol Immunol | The role of neutrophils in the development of liver diseases. | 2014 | Details |
| A47163 | 24581955 | Alcohol | Influence of fat/carbohydrate ratio on progression of fatty liver disease and on development of osteopenia in male rats fed alcohol via total enteral nutrition (TEN). | 2014 | Details |
| A47164 | 24513924 | Food Funct | Polyphenol-rich extract of Nelumbo nucifera leaves inhibits alcohol-induced steatohepatitis via reducing hepatic lipid accumulation and anti-inflammation in C57BL/6J mice. | 2014 | Details |
| A47165 | 24456360 | J Med Food | Schisandra chinensis prevents alcohol-induced fatty liver disease in rats. | 2014 | Details |
| A47166 | 24430730 | Sci Rep | Disturbances in the murine hepatic circadian clock in alcohol-induced hepatic steatosis. | 2014 | Details |
| A47167 | 24417906 | Gastroenterol Hepatol | [Comparison of the M and XL FibroScan(®) probes to estimate liver stiffness by transient elastography]. | 2014 | Details |
| A47168 | 24396389 | Clin Dev Immunol | Anti-IL-17 antibody improves hepatic steatosis by suppressing interleukin-17-related fatty acid synthesis and metabolism. | 2013 | Details |
| A47169 | 24392995 | Int J Food Sci Nutr | Effects of polysaccharide from fruiting bodies of Agaricus bisporus, Agaricus brasiliensis, and Phellinus linteus on alcoholic liver injury. | 2014 | Details |
| A47170 | 24269941 | Cell Signal | β-Lapachone alleviates alcoholic fatty liver disease in rats. | 2013 | Details |
| A47171 | 24269813 | Biochem Biophys Res Commun | Activation of farnesoid X receptor attenuates hepatic injury in a murine model of alcoholic liver disease. | 2013 | Details |
| A47172 | 24262277 | Gastroenterology | Deletion of SIRT1 from hepatocytes in mice disrupts lipin-1 signaling and aggravates alcoholic fatty liver. | 2013 | Details |
| A47173 | 24214181 | Hepatology | Osteopontin binding to lipopolysaccharide lowers tumor necrosis factor-α and prevents early alcohol-induced liver injury in mice. | 2014 | Details |
| A47174 | 24206787 | BMC Med Genomics | ChIP-seq in steatohepatitis and normal liver tissue identifies candidate disease mechanisms related to progression to cancer. | 2013 | Details |
| A47175 | 24171385 | J Agric Food Chem | Metabolomics of ginger essential oil against alcoholic fatty liver in mice. | 2013 | Details |
| A47176 | 24155903 | PLoS One | Dietary zinc deficiency exaggerates ethanol-induced liver injury in mice: involvement of intrahepatic and extrahepatic factors. | 2013 | Details |
| A47177 | 24146112 | Arch Toxicol | Protective effects of dioscin against alcohol-induced liver injury. | 2013 | Details |
| A47178 | 24117505 | Alcohol Clin Exp Res | Rab GTPases associate with isolated lipid droplets (LDs) and show altered content after ethanol administration: potential role in alcohol-impaired LD metabolism. | 2013 | Details |
| A47179 | 24086266 | PLoS One | Hepatocyte expression of the senescence marker p21 is linked to fibrosis and an adverse liver-related outcome in alcohol-related liver disease. | 2013 | Details |
| A47180 | 24063989 | Life Sci | Low doses of curcumin protect alcohol-induced liver damage by modulation of the alcohol metabolic pathway, CYP2E1 and AMPK. | 2013 | Details |
| A47181 | 24020403 | Int J Exp Pathol | Experimental rat model for alcohol-induced osteonecrosis of the femoral head. | 2013 | Details |
| A47182 | 23969550 | Alcohol Alcohol | Sex-specific differences in the development of acute alcohol-induced liver steatosis in mice. | 2013 | Details |
| A47183 | 23958271 | Trials | Steroids or pentoxifylline for alcoholic hepatitis (STOPAH): study protocol for a randomised controlled trial. | 2013 | Details |
| A47184 | 23922897 | PLoS One | Acetaldehyde-derived advanced glycation end-products promote alcoholic liver disease. | 2013 | Details |
| A47185 | 23907024 | Food Chem Toxicol | A role for lipid rafts in the protection afforded by docosahexaenoic acid against ethanol toxicity in primary rat hepatocytes. | 2013 | Details |
| A47186 | 23815146 | Nutr Rev | Ethanol metabolism and its effects on the intestinal epithelial barrier. | 2013 | Details |
| A47187 | 23799218 | J Gastrointestin Liver Dis | Update on the management of alcoholic steatohepatitis. | 2013 | Details |
| A47188 | 23798569 | Dis Model Mech | Ethanol metabolism and oxidative stress are required for unfolded protein response activation and steatosis in zebrafish with alcoholic liver disease. | 2013 | Details |
| A47189 | 23707365 | J Hepatol | ASMase is required for chronic alcohol induced hepatic endoplasmic reticulum stress and mitochondrial cholesterol loading. | 2013 | Details |
| A47190 | 23697887 | Zebrafish | Defining hepatic dysfunction parameters in two models of fatty liver disease in zebrafish larvae. | 2013 | Details |
| A47191 | 23682678 | Liver Int | Circulating MicroRNAs as potential biomarkers for alcoholic steatohepatitis. | 2013 | Details |
| A47192 | 23646923 | Br J Pharmacol | Activation of NF-κB after chronic ethanol intake and haemorrhagic shock/resuscitation in mice. | 2013 | Details |
| A47193 | 23641075 | J Cell Sci | Lamin aggregation is an early sensor of porphyria-induced liver injury. | 2013 | Details |
| A47194 | 23422163 | J Mol Cell Cardiol | Chronic ethanol consumption increases cardiomyocyte fatty acid uptake and decreases ventricular contractile function in C57BL/6J mice. | 2013 | Details |
| A47195 | 23408358 | Hepatology | Deficiency of intestinal mucin-2 ameliorates experimental alcoholic liver disease in mice. | 2013 | Details |
| A47196 | 23337955 | Int J Mol Med | Analysis of differentially expressed genes and microRNAs in alcoholic liver disease. | 2013 | Details |
| A47197 | 23277536 | J Pharmacol Exp Ther | Puerarin ameliorates experimental alcoholic liver injury by inhibition of endotoxin gut leakage, Kupffer cell activation, and endotoxin receptors expression. | 2012 | Details |
| A47198 | 23274539 | Food Chem Toxicol | α-Terpineol induces fatty liver in mice mediated by the AMP-activated kinase and sterol response element binding protein pathway. | 2012 | Details |
| A47199 | 23206305 | Zhonghua Gan Zang Bing Za Zhi | [Changes in the intestinal microenvironment during development of alcoholic fatty liver disease and related effects of probiotic therapy]. | 2012 | Details |
| A47200 | 23058988 | J Ethnopharmacol | Herbal medicines for the prevention of alcoholic liver disease: a review. | 2012 | Details |
| A47201 | 23025051 | Eksp Klin Farmakol | [Hepatoprotective and immunomodulatory effects of infliximab on experimental alcoholic steatohepatitis]. | 2012 | Details |
| A47202 | 23023014 | J Hepatol | Activation of toll-like receptor 3 attenuates alcoholic liver injury by stimulating Kupffer cells and stellate cells to produce interleukin-10 in mice. | 2012 | Details |
| A47203 | 23010494 | Free Radic Biol Med | Hepatic mitochondrial dysfunction induced by fatty acids and ethanol. | 2012 | Details |
| A47204 | 22988930 | J Gastroenterol Hepatol | Chronic alcohol-induced hepatic insulin resistance and endoplasmic reticulum stress ameliorated by peroxisome-proliferator activated receptor-δ agonist treatment. | 2013 | Details |
| A47205 | 22988723 | Rev Med Suisse | [Alcoholic steatohepatitis: what's new in 2012?]. | 2012 | Details |
| A47206 | 22905112 | PLoS One | Reduced susceptibility of DNA methyltransferase 1 hypomorphic (Dnmt1N/+) mice to hepatic steatosis upon feeding liquid alcohol diet. | 2012 | Details |
| A47207 | 22902304 | Gene | Genetic variants of TNFα, IL10, IL1β, CTLA4 and TGFβ1 modulate the indices of alcohol-induced liver injury in East Indian population. | 2012 | Details |
| A47208 | 22861370 | Clin Exp Immunol | Hepatic expression of CCL2 in alcoholic liver disease is associated with disease severity and neutrophil infiltrates. | 2012 | Details |
| A47209 | 22841822 | Am J Pathol | Leptin deficiency contributes to the pathogenesis of alcoholic fatty liver disease in mice. | 2012 | Details |
| A47210 | 22841474 | Am J Pathol | Epigenetic regulation of miR-34a expression in alcoholic liver injury. | 2012 | Details |
| A47211 | 22745073 | Am J Chin Med | Protective effects of total flavonoids from Litsea coreana on alcoholic fatty liver in rats associated with down-regulation adipose differentiation-related protein expression. | 2012 | Details |
| A47212 | 22684045 | Gastroenterology | β-Catenin regulates hepatic mitochondrial function and energy balance in mice. | 2012 | Details |
| A47213 | 22676331 | Alcohol Clin Exp Res | Thromboxane inhibitors attenuate inflammatory and fibrotic changes in rat liver despite continued ethanol administrations. | 2012 | Details |
| A47214 | 22564350 | Redox Rep | Ascorbic acid supplementation causes faster restoration of reduced glutathione content in the regression of alcohol-induced hepatotoxicity in male guinea pigs. | 2012 | Details |
| A47215 | 22538404 | Am J Physiol Gastrointest Liver Physiol | Arachidonic acid stimulates TNFα production in Kupffer cells via a reactive oxygen species-pERK1/2-Egr1-dependent mechanism. | 2012 | Details |
| A47216 | 22532405 | Mol Biosyst | Metabolic profiling of an alcoholic fatty liver in zebrafish (Danio rerio). | 2012 | Details |
| A47217 | 22504843 | Food Chem Toxicol | Hepatoprotective effects of dieckol-rich phlorotannins from Ecklonia cava, a brown seaweed, against ethanol induced liver damage in BALB/c mice. | 2012 | Details |
| A47218 | 22504185 | Gastroenterology | MicroRNAs in liver disease. | 2012 | Details |
| A47219 | 22490057 | Aliment Pharmacol Ther | Cirrhosis and mortality risks of biopsy-verified alcoholic pure steatosis and steatohepatitis: a nationwide registry-based study. | 2012 | Details |
| A47220 | 22481461 | Ann Hepatol | Hepatic hemodynamics and transient elastography in alcoholic foamy degeneration: report of 2 cases. | 2012 | Details |
| A47221 | 22425478 | Presse Med | [Current trends in liver biopsy indications in chronic liver diseases]. | 2012 | Details |
| A47222 | 22413959 | Alcohol Clin Exp Res | Carvedilol attenuates the progression of alcohol fatty liver disease in rats. | 2012 | Details |
| A47223 | 22380651 | Immunopharmacol Immunotoxicol | Aliphatic alcohols of illegally produced spirits can act synergistically on superoxide-anion production by human granulocytes. | 2012 | Details |
| A47224 | 22356308 | J Dig Dis | Oxidative stress and redox signaling mechanisms of alcoholic liver disease: updated experimental and clinical evidence. | 2012 | Details |
| A47225 | 22320921 | J Gastroenterol Hepatol | Retinoic acids and hepatic stellate cells in liver disease. | 2012 | Details |
| A47226 | 22273278 | Alcohol Clin Exp Res | Inhibition of apoptosis protects mice from ethanol-mediated acceleration of early markers of CCl4 -induced fibrosis but not steatosis or inflammation. | 2012 | Details |
| A47227 | 22234172 | Am J Pathol | Chronic alcohol exposure stimulates adipose tissue lipolysis in mice: role of reverse triglyceride transport in the pathogenesis of alcoholic steatosis. | 2012 | Details |
| A47228 | 22208561 | Lipids Health Dis | Activation of peroxisome proliferator activated receptor alpha ameliorates ethanol induced steatohepatitis in mice. | 2011 | Details |
| A47229 | 22206017 | PLoS One | Neonatal androgenization exacerbates alcohol-induced liver injury in adult rats, an effect abrogated by estrogen. | 2011 | Details |
| A47230 | 22169690 | Zhonghua Yu Fang Yi Xue Za Zhi | [The effects of NF-E2-related factor-2 prompter polymorphism on alcoholic liver disease with Vibrio vulnificus sepsis]. | 2011 | Details |
| A47231 | 22150916 | Hepatol Res | Roles of gender, obesity, and lifestyle-related diseases in alcoholic liver disease: Obesity does not influence the severity of alcoholic liver disease. | 2011 | Details |
| A47232 | 22035247 | BMC Gastroenterol | Early liver biopsy, intraparenchymal cholestasis, and prognosis in patients with alcoholic steatohepatitis. | 2011 | Details |
| A47233 | 22013387 | J Biomed Biotechnol | Antilipogenic and anti-inflammatory activities of Codonopsis lanceolata in mice hepatic tissues after chronic ethanol feeding. | 2011 | Details |
| A47234 | 21913943 | Alcohol Clin Exp Res | Housekeeping gene variability in the liver of alcoholic patients. | 2011 | Details |
| A47235 | 21896344 | J Hepatol | HIF-1α induction suppresses excessive lipid accumulation in alcoholic fatty liver in mice. | 2011 | Details |
| A47236 | 21856784 | J Lipid Res | Altered hepatic lipid metabolism in C57BL/6 mice fed alcohol: a targeted lipidomic and gene expression study. | 2011 | Details |
| A47237 | 21826088 | Nat Rev Gastroenterol Hepatol | Alcoholic liver disease: pathogenesis and new targets for therapy. | 2011 | Details |
| A47238 | 21819471 | Addiction | Alcohol consumption and non-communicable diseases: epidemiology and policy implications. | 2011 | Details |
| A47239 | 21790669 | Alcohol Clin Exp Res | Limited therapeutic effect of N-acetylcysteine on hepatic insulin resistance in an experimental model of alcohol-induced steatohepatitis. | 2011 | Details |
| A47240 | 21763219 | J Chromatogr B Analyt Technol Biomed Life Sci | Metabolomics study of alcohol-induced liver injury and hepatocellular carcinoma xenografts in mice. | 2011 | Details |
| A47241 | 21708146 | Exp Mol Pathol | Betaine feeding prevents the blood alcohol cycle in rats fed alcohol continuously for 1 month using the rat intragastric tube feeding model. | 2011 | Details |
| A47242 | 21673994 | PLoS One | Catechin suppresses an array of signalling molecules and modulates alcohol-induced endotoxin mediated liver injury in a rat model. | 2011 | Details |
| A47243 | 21663494 | J Med Food | Hepatoprotective effect of aged black garlic on chronic alcohol-induced liver injury in rats. | 2011 | Details |