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  • human proteome microarray

    Jing Zhong, Shanghai University of Traditional Chinese Medicine, 2023.08.12

    Description

    The median fluorescence signal at each site (F635_Median) was divided by the background (B635_Median) for data analysis, that is, original signal strength (I) = F635_Median/B635_Median. The median and SD of I were calculated to obtain the corrected data Z-Score (corrected signal strength) for each site. Proteins with a Z-Score greater than 2.8 were those that bind to HDCA. The mean value (I mean) represents the mean value of the original signal strength of each protein. I Mean-Ratio is the ratio between the Biotin-HDCA group and Biotin group. To call the candidates, the cutoff was set as a P value≤0.05 and I Mean-Ratio≥1.4.

    Analysis type

    De Novo Assembly

    OEZ014266

  • OEZ_Wenyun_2307281403

    Wenyun Guo, , 2023.07.28

    Analysis type

    De Novo Assembly

    OEZ014264

  • Single cell gene_expression

    Mao Zhang, , 2023.02.16

    Analysis type

    Other

    OEZ013253

  • Acid mine drainage virome

    Zhenghua Liu, , 2021.12.08

    Description

    Viral sequences identified from metagenomes and genomes data across global acid mine drainage.

    Analysis type

    Sequence Annotation

    OEZ008166

  • SMAG_MAGs

    Caiyu Lu, , 2023.06.14

    Description

    SMAG catalog

    Analysis type

    Other

    OEZ014109

  • gene_express

    fan wang, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, 2023.06.18

    Analysis type

    Other

    OEZ014114

  • Analysis of blood methylation quantitative trait loci in East Asians identifies ancestry-specific effects associated with complex trait variation

    Sijia Wang, , 2021.11.16

    Description

    Methylation quantitative trait loci (mQTLs) are essential for understanding the role of DNA methylation changes in genetic predisposition, yet they have not been fully characterized in East Asians. We identified mQTLs in whole blood from 3,523 Chinese individuals and replicated them in additional 1,858 Chinese individuals from two cohorts. Over 9% of mQTLs displayed specificity to East-Asians, facilitating the fine-mapping of EA-specific genetic associations, as shown for variants associated with height. Trans-mQTLs hotspots revealed biological pathways contributing to EA-specific genetic associations, including an ERG-mediated 233 trans-mCpG network, implicated in hematopoietic cell differentiation, which reflects binding efficiency modulation of the ERG protein complex. More than 90% of mQTLs were shared between different blood cell-lineages, with the smaller fraction of lineage-specific mQTLs displaying preferential hypomethylation in the respective lineages. Our study provides new insights into the mQTL landscape across ethnicities and their downstream effects on cellular processes and diseases/traits.

    Analysis type

    Other

    OEZ008120

  • PMN.rds

    Yiwei Meng, CEMCS, 2023.06.13

    Analysis type

    Other

    OEZ014108

  • PMN_rawcounts.mtx.gz

    Yiwei Meng, CEMCS, 2023.06.13

    Analysis type

    Other

    OEZ014107

  • PMN_meta_data.csv

    Yiwei Meng, CEMCS, 2023.06.13

    Analysis type

    Other

    OEZ014106