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  • OEZ_QL

    QL Q, , 2024.06.06

    Analysis type

    Other

    OEZ017522

  • OEZ_Xin_2405271105

    Xin Li, , 2024.05.27

    Analysis type

    De Novo Assembly

    OEZ017515

  • Free-living Healthy Cohort

    Zheng Lab, , 2024.05.07

    Analysis type

    Other

    OEZ017069

  • OEZ_Ruolin_2405161055

    Ruolin Cheng, , 2024.05.16

    Analysis type

    Other

    OEZ017513

  • Analysis of blood methylation quantitative trait loci in East Asians identifies ancestry-specific effects associated with complex trait variation

    Sijia Wang, , 2021.11.16

    Description

    Methylation quantitative trait loci (mQTLs) are essential for understanding the role of DNA methylation changes in genetic predisposition, yet they have not been fully characterized in East Asians. We identified mQTLs in whole blood from 3,523 Chinese individuals and replicated them in additional 1,858 Chinese individuals from two cohorts. Over 9% of mQTLs displayed specificity to East-Asians, facilitating the fine-mapping of EA-specific genetic associations, as shown for variants associated with height. Trans-mQTLs hotspots revealed biological pathways contributing to EA-specific genetic associations, including an ERG-mediated 233 trans-mCpG network, implicated in hematopoietic cell differentiation, which reflects binding efficiency modulation of the ERG protein complex. More than 90% of mQTLs were shared between different blood cell-lineages, with the smaller fraction of lineage-specific mQTLs displaying preferential hypomethylation in the respective lineages. Our study provides new insights into the mQTL landscape across ethnicities and their downstream effects on cellular processes and diseases/traits.

    Analysis type

    Other

    OEZ008120

  • Mouse serum metabolomic

    Zheng Lab, , 2024.05.07

    Analysis type

    Other

    OEZ017068

  • GWAS of nail plate morphology

    MengXiang You, , 2024.04.21

    Description

    Summary statistics of "Genetic Loci Associated with Nail Plate Morphology in East Asian Populations"

    Analysis type

    De Novo Assembly

    OEZ017061

  • T-ALL RNA-seq

    Yuting Dai, , 2024.04.26

    Analysis type

    Other

    OEZ017063

  • OEZ_Tao_2404242147

    Tao Zeng, , 2024.04.24

    Description

    RNA-seq and ATAC-seq data for investigating p38-MAPK signaling in MASLD-Associated Hepatocellular Carcinoma and other etiologies

    Analysis type

    Reference Alignment

    OEZ017062

  • chr17 CN value

    Peiwei Chai, , 2024.04.07

    Analysis type

    De Novo Assembly

    OEZ014878