Project IDOEP004750
Project NameEMSY enhances cancer stem cell self-renewal and tumorigenesis by reshaping methionine metabolism in triple-negative breast cancer
Experiment TypeGenomic
ProtocolBriefly, 107 to 108 TNBC cells (Control or EMSY) were harvested, crosslinking was performed with 1% formaldehyde or 1% paraformaldehyde for 10 minutes. To enhance cell lysis, we ran the lysate through a 27g needle three times and flash froze it in −80°C. Sonication was then performed with the Misonix 4000 water bath sonication unit at 15% amplitude for 20 minutes. Protein/DNA complex was precipitated by specific antibodies against H3K4me2/3 (CST) and IgG control (Millipore, Burlington, MA, USA). DNA was purified using DNA Purification Kit (Qiagen, Hilden, Germany). PCR was performed using Phusion High Fidelity PCR master mix. ChIP-enriched chromatins were sequenced on Illumina HiSeq 2000 platforms according to the manufacture’s protocol.
OEX025490
Project IDOEP004748
Project NameKRAS-G12V mRNA Vaccine and Pembrolizumab in Advanced Solid Tumors: Case report
Experiment TypeGenomic
OEX025487
Project IDOEP004748
Project NameKRAS-G12V mRNA Vaccine and Pembrolizumab in Advanced Solid Tumors: Case report
Experiment TypeGenomic
OEX025488
Project IDOEP004748
Project NameKRAS-G12V mRNA Vaccine and Pembrolizumab in Advanced Solid Tumors: Case report
Experiment TypeGenomic
OEX025486
Project IDOEP004747
Project Name20231117_rawdata
Experiment TypeGenomic
OEX025485
Project IDOEP004742
Project NameSpatial transcriptomics analysis of tumor microenvironment in Epstein-Barr virus (EBV)-positive diffuse large B-cell lymphoma (DLBCL
Experiment TypeTranscriptomic
OEX025480
Project IDOEP004700
Project NameProteomic and phospho-proteomic raw data of Wilms' tumor tissue and normal adjacent kidney tissue.
Experiment TypeProteomic
ProtocolTMT 6-plex shotgun proteomics was performed on Wilms' tumor tissue and normal adjacent kidney tissue from Wilms tumor patients using a Q Exactive™ Plus mass spectrometer (Thermo Fisher Scientific). Each experiment has two technical replications.
OEX025368
Project IDOEP004700
Project NameProteomic and phospho-proteomic raw data of Wilms' tumor tissue and normal adjacent kidney tissue.
Experiment TypeGenomic
OEX025392
Project IDOEP004700
Project NameProteomic and phospho-proteomic raw data of Wilms' tumor tissue and normal adjacent kidney tissue.
Experiment TypeProteomic
ProtocolLabel-free Phospho-proteomic was performed on Wilms' tumor tissue and normal adjacent kidney tissue from Wilms tumor patients using a Q Exactive™ Plus mass spectrometer (Thermo Fisher Scientific).
OEX025369
Project IDOEP004731
Project NameGenomics of lacustrine Roseobacteraceae isolates from Tibetan Plateau lakes
Experiment TypeGenomic
ProtocolGenomic DNA was extracted using the Wizard Genomic DNA Purification Kit (Promega) and subse-quently sequenced on the Illumina Miseq platform (Shanghai Biozeron Biotechnology Co., Ltd).
OEX025396