General Information
- Project ID
- OEP000012
- Project Name
- Transcription factor Sox30 during germ cell development
- Description
- Genetic depletion of transcription factor Sox30 using CRISPR-Cas9 gene editing technology leads to defects in spermiogenesis, and uniformly arrested at early round spermatids. Specifically, in the absence of Sox30, proacrosomic vesicles fail to form a single acrosomal organelle. This is correlated with changes in postmeiotic gene expression.
- Publications
-
Sox30 initiates transcription of haploid genes during late meiosis and spermiogenesis in mouse testes
Bai, S., Fu, K., Yin, H., Cui, Y., Yue, Q., & Li, W., et al. (2018). Sox30 initiates transcription of haploid genes during late meiosis and spermiogenesis in mouse testes. Development.
(PMID: 29866902) (DOI: 10.1242/dev.164855)
Project information
- Experiments
- 2
- Samples
- 12
Sample ID Sample Name Sample Subject Type Organism Tissue Create Date OES000055 Testis_WT_rep1_RNAseq Animalia Mus musculus testis 2018-04-27 OES000056 Testis_WT_rep2_RNAseq Animalia Mus musculus testis 2018-04-27 OES000057 Testis_WT_rep3_RNAseq Animalia Mus musculus testis 2018-04-27 OES000058 Testis_KO_rep1_RNAseq Animalia Mus musculus testis 2018-04-27 OES000059 Testis_KO_rep2_RNAseq Animalia Mus musculus testis 2018-04-27 OES000060 Testis_KO_rep3_RNAseq Animalia Mus musculus testis 2018-04-27 OES000061 PS_WT_RNAseq Animalia Mus musculus testis 2018-04-27 OES000062 PS_KO_RNAseq Animalia Mus musculus testis 2018-04-27 OES000063 RS_WT_RNAseq Animalia Mus musculus testis 2018-04-27 OES000064 RS_KO_RNAseq Animalia Mus musculus testis 2018-04-27 OES000065 Sox30 ChIP-seq (Wild Type) Animalia Mus musculus testis 2018-04-27 OES000066 Input ChIP-seq (Wild Type) Animalia Mus musculus testis 2018-04-27 - Runs
-
12
Run ID Run Name Experiment Sample Data Num Create Date OER000137 OER_Lan_1804271347 OEX000019 OES000055 1 2018-04-27 OER000138 OER_Lan_1804271409 OEX000019 OES000056 1 2018-04-27 OER000139 OER_Lan_1804271411 OEX000019 OES000057 1 2018-04-27 OER000140 OER_Lan_1804271412 OEX000019 OES000058 1 2018-04-27 OER000141 OER_Lan_1804271414 OEX000019 OES000059 1 2018-04-27 OER000142 OER_Lan_1804271415 OEX000019 OES000060 1 2018-04-27 OER000143 OER_Lan_1804271513 OEX000019 OES000061 1 2018-04-27 OER000144 OER_Lan_1804271516 OEX000019 OES000062 1 2018-04-27 OER000145 OER_Lan_1804271516 OEX000019 OES000063 1 2018-04-27 OER000146 OER_Lan_1804271519 OEX000019 OES000064 1 2018-04-27 OER000147 OER_Lan_1804271527 OEX000020 OES000065 1 2018-04-27 OER000148 OER_Lan_1804271528 OEX000020 OES000066 1 2018-04-27
Author Information
- Create Date
- 2018-04-27
- Last Modified
- 2018-12-26
- Submission
- Lan Ye
- Nanjing Medical University