General Information
- Project ID
- OEP000118
- Project Name
- Whole-exome mutational and transcriptional landscapes of combined hepatocellular cholangiocarcinoma and intrahepatic cholangiocarcinoma reveal molecular diversity
- Description
- Primary liver cancer (PLC) is the third largest contributor to cancer mortality in the world. PLC is a heterogeneous disease that encompasses several biologically distinct subtypes including hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC) and combined hepatocellular-cholangiocarcinoma (CHC). CHC is a distinct, albeit rare, subtype of PLC and is comprised of cells with histopathological features of both HCC and ICC. Several studies have focused on the mutation and expression landscapes of HCC and ICC. However studies of CHC were rare. The aim of the current study was to identify genetic and gene expression alterations in the carcinogenesis and development of CHC and ICC in the Chinese population. Unraveling both similar and differing patterns among these subtypes may help to identify personalized medicine approaches that could improve patient survival.
- Used ID
- NODEP00371762  
- Publications
-
Whole-exome mutational and transcriptional landscapes of combined hepatocellular cholangiocarcinoma and intrahepatic cholangiocarcinoma reveal molecular diversity
Liu Z H, Lian B F, Dong Q Z, et al. Whole-exome mutational and transcriptional landscapes of combined hepatocellular cholangiocarcinoma and intrahepatic cholangiocarcinoma reveal molecular diversity[J].
(PMID: 29408647) (DOI: 10.1016/j.bbadis.2018.01.027)
Project information
- Experiments
- 2
- Samples
- 37
Sample ID Sample Name Sample Subject Type Organism Tissue Create Date OES004850 CHC1A Human Homo sapiens liver 2018-01-18 OES004851 CHC1B Human Homo sapiens liver 2018-01-18 OES004852 CHC2A Human Homo sapiens liver 2018-01-18 OES004853 CHC2B Human Homo sapiens liver 2018-01-18 OES004854 CHC3A Human Homo sapiens liver 2018-01-18 OES004855 CHC3B Human Homo sapiens liver 2018-01-18 OES004856 CHC4A Human Homo sapiens liver 2018-01-18 OES004857 CHC4B Human Homo sapiens liver 2018-01-18 OES004858 CHC5A Human Homo sapiens liver 2018-01-18 OES004859 CHC5B Human Homo sapiens liver 2018-01-18 OES004860 CHC6A Human Homo sapiens liver 2018-01-18 OES004861 CHC6B Human Homo sapiens liver 2018-01-18 OES004862 CHC7A Human Homo sapiens liver 2018-01-18 OES004863 CHC7B Human Homo sapiens liver 2018-01-18 OES004864 CHC8A Human Homo sapiens liver 2018-01-18 OES004865 CHC8B Human Homo sapiens liver 2018-01-18 OES004866 CHC9A Human Homo sapiens liver 2018-01-18 OES004867 CHC9B Human Homo sapiens liver 2018-01-18 OES004868 CHC10A Human Homo sapiens liver 2018-01-18 OES004869 CHC10B Human Homo sapiens liver 2018-01-18 OES004870 ICC1A Human Homo sapiens liver 2018-01-18 OES004871 ICC1B Human Homo sapiens liver 2018-01-18 OES004874 ICC3A Human Homo sapiens liver 2018-01-18 OES004875 ICC3B Human Homo sapiens liver 2018-01-18 OES004876 ICC4A Human Homo sapiens liver 2018-01-18 OES004877 ICC4B Human Homo sapiens liver 2018-01-18 OES004878 ICC5A Human Homo sapiens liver 2018-01-18 OES004879 ICC5B Human Homo sapiens liver 2018-01-18 OES004880 ICC6A Human Homo sapiens liver 2018-01-18 OES004881 ICC6B Human Homo sapiens liver 2018-01-18 OES004882 ICC7A Human Homo sapiens liver 2018-01-18 OES004883 ICC7B Human Homo sapiens liver 2018-01-18 OES004884 ICC8A Human Homo sapiens liver 2018-01-18 OES004886 ICC9A Human Homo sapiens liver 2018-01-18 OES004887 ICC9B Human Homo sapiens liver 2018-01-18 OES004888 ICC10A Human Homo sapiens liver 2018-01-18 OES004889 ICC10B Human Homo sapiens liver 2018-01-18 - Runs
-
46
Run ID Run Name Experiment Sample Data Num Create Date OER010062 NODER_Zhenhao_1801191329_CHC1A OEX001436 OES004850 2 2018-01-19 OER010063 NODER_Zhenhao_1801221049_CHC2A OEX001436 OES004852 2 2018-01-22 OER010064 NODER_Zhenhao_1801221050_CHC3A OEX001436 OES004854 2 2018-01-22 OER010065 NODER_Zhenhao_1801221052_CHC4A OEX001436 OES004856 2 2018-01-22 OER010066 NODER_Zhenhao_1801221052_CHC5A OEX001436 OES004858 2 2018-01-22 OER010067 NODER_Zhenhao_1801221052_CHC6A OEX001436 OES004860 2 2018-01-22 OER010068 NODER_Zhenhao_1801221054_CHC7A OEX001436 OES004862 2 2018-01-22 OER010069 NODER_Zhenhao_1801221054_CHC8A OEX001436 OES004884 2 2018-01-22 OER010070 NODER_Zhenhao_1801221055_CHC9A OEX001436 OES004866 2 2018-01-22 OER010071 NODER_Zhenhao_1801221055_CHC10A OEX001436 OES004888 2 2018-01-22 OER010072 NODER_Zhenhao_1801221056_RNA_CHC1 OEX001437 OES004850 2 2018-01-22 OER010073 NODER_Zhenhao_1801221056_RNA_CHC1 OEX001437 OES004851 2 2018-01-22 OER010074 NODER_Zhenhao_1801221058_RNA_CHC2 OEX001437 OES004852 2 2018-01-22 OER010075 NODER_Zhenhao_1801221058_RNA_CHC2 OEX001437 OES004853 2 2018-01-22 OER010076 NODER_Zhenhao_1801221059_RNA_CHC3 OEX001437 OES004854 2 2018-01-22 OER010077 NODER_Zhenhao_1801221059_RNA_CHC3 OEX001437 OES004855 2 2018-01-22 OER010078 NODER_Zhenhao_1801221101_RNA_CHC4 OEX001437 OES004856 2 2018-01-22 OER010079 NODER_Zhenhao_1801221101_RNA_CHC4 OEX001437 OES004857 2 2018-01-22 OER010080 NODER_Zhenhao_1801221102_RNA_CHC5 OEX001437 OES004858 2 2018-01-22 OER010081 NODER_Zhenhao_1801221102_RNA_CHC5 OEX001437 OES004859 2 2018-01-22 OER010082 NODER_Zhenhao_1801221103_RNA_CHC6 OEX001437 OES004860 2 2018-01-22 OER010083 NODER_Zhenhao_1801221103_RNA_CHC6 OEX001437 OES004861 2 2018-01-22 OER010084 NODER_Zhenhao_1801221105_RNA_CHC7 OEX001437 OES004862 2 2018-01-22 OER010085 NODER_Zhenhao_1801221105_RNA_CHC7 OEX001437 OES004863 2 2018-01-22 OER010086 NODER_Zhenhao_1801221108_RNA_CHC8 OEX001437 OES004864 2 2018-01-22 OER010087 NODER_Zhenhao_1801221108_RNA_CHC8 OEX001437 OES004865 2 2018-01-22 OER010088 NODER_Zhenhao_1801221110_RNA_CHC9 OEX001437 OES004866 2 2018-01-22 OER010089 NODER_Zhenhao_1801221110_RNA_CHC9 OEX001437 OES004867 2 2018-01-22 OER010090 NODER_Zhenhao_1801221111_RNA_CHC10 OEX001437 OES004868 2 2018-01-22 OER010091 NODER_Zhenhao_1801221111_RNA_CHC10 OEX001437 OES004869 2 2018-01-22 OER010092 NODER_Zhenhao_1801221112_RNA_ICC1 OEX001437 OES004870 2 2018-01-22 OER010093 NODER_Zhenhao_1801221112_RNA_ICC1 OEX001437 OES004871 2 2018-01-22 OER010094 NODER_Zhenhao_1801221116_RNA_ICC3 OEX001437 OES004874 2 2018-01-22 OER010095 NODER_Zhenhao_1801221116_RNA_ICC3 OEX001437 OES004875 2 2018-01-22 OER010096 NODER_Zhenhao_1801221116_RNA_ICC4 OEX001437 OES004876 2 2018-01-22 OER010097 NODER_Zhenhao_1801221116_RNA_ICC4 OEX001437 OES004877 2 2018-01-22 OER010098 NODER_Zhenhao_1801221117_RNA_ICC5 OEX001437 OES004878 2 2018-01-22 OER010099 NODER_Zhenhao_1801221117_RNA_ICC5 OEX001437 OES004879 2 2018-01-22 OER010100 NODER_Zhenhao_1801221118_RNA_ICC6 OEX001437 OES004880 2 2018-01-22 OER010101 NODER_Zhenhao_1801221118_RNA_ICC6 OEX001437 OES004881 2 2018-01-22 OER010102 NODER_Zhenhao_1801221122_RNA_ICC7 OEX001437 OES004882 2 2018-01-22 OER010103 NODER_Zhenhao_1801221122_RNA_ICC7 OEX001437 OES004883 2 2018-01-22 OER010104 NODER_Zhenhao_1801221123_RNA_ICC9 OEX001437 OES004886 2 2018-01-22 OER010105 NODER_Zhenhao_1801221123_RNA_ICC9 OEX001437 OES004887 2 2018-01-22 OER010106 NODER_Zhenhao_1801221124_RNA_ICC10 OEX001437 OES004888 2 2018-01-22 OER010107 NODER_Zhenhao_1801221124_RNA_ICC10 OEX001437 OES004889 2 2018-01-22
Author Information
- Create Date
- 2018-01-18
- Last Modified
- 2023-12-01
- Submission
- Zhenhao Liu
- SCBIT