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  • PROJ plastisphere MAGs

    Qian Yang, CAS,2023.08.29

    Description

    OEP004489

  • PROJ mangrove plastisphere2

    Qian Yang, CAS,2023.08.29

    Description

    OEP004488

  • PROJ mangrove plastisphere

    Qian Yang, CAS,2023.08.29

    Description

    OEP004485

  • PROJ Bacterial community diversity of lake sediments in China

    Qinglong Wu, Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences,2021.01.12

    Description

    IW（Inner Water)

    OEP001556

  • PROJ Spatial and single-cell transcriptomics landscape of adenomyosis

    Guihua Liu, The Sixth Affiliated Hospital of Sun Yat-sen University,2023.05.26

    Description

    Adenomyosis is a prevalent and non-cancerous uterine disease which can significantly impaired the fertility of reproductive-age women. However, the etiology, as well as the cellular and molecular mechanism underlying adenomyosis remain largely unknown. Here, we utilized cutting-edge spatial and single-cell RNA sequencing technologies to create a comprehensive transcriptional atlas of adenomyosis pathology. Our spatial profiling clearly distinguished gland, mesenchyma and myometrium regions, recapitulating spatial transcriptome structural characteristics of uterus. Moreover, we analyzed the expression profiles of 69,115 single cells and integrated them with spatial data. The analysis of immune cells showed a distinct immune inflammatory microenvironment in the eutopic and ectopic endometrial glands of adenomyosis. Notably, we discovered an increased number of DNAH9+ ciliated cells in ectopic endometrial glands, indicating their potential role in the formation of ectopic endometrium. These findings provide cellular evidence to support the invagination theory and offer a new vision on the pathophysiology and clinical intervention of adenomyosis.

    OEP004165

  • PROJ FUSCC_TNBC_scRNA

    Ding Ma, Fudan University Shanghai cancer center,2022.05.21

    Description

    Here, we performed single-cell RNA sequencing of pre-treatment tumor samples in 26 patients with early-stage TNBC and 6 patients with advanced TNBC to define anti-PD-1 response-related components in the tumor microenvironment. Also, we performed RNA sequencing of pre-treatment tumor samples in 60 patients with early-stage TNBC receiving neoadjuvant anti-PD1 treatment.

    OEP003394

  • PROJ 16S rRNA gene diversity during DOES incubation under different HHP

    Yu Zhang, Shanghai Jiaotong University,2023.03.13

    Description

    The microbial diversity of hadal sediment from the Mariana Trench with increasing high hydrostatic pressure (HHP; 0.1, 40, 70, 90 and 115 MPa) during incubation using the (deep ocean experimental simulator) DOES system at a flow rate of 0.3 mL/min.

    OEP004015

  • PROJ JScovid19

    Zheng Lab, Fudan univerisity,2021.08.09

    Description

    OEP002590

  • PROJ mRNA expression in advanced NSCLC

    Xiaoxi Cheng, Chinese Academy of Medical Sciences,2023.09.11

    Description

    The dataset contains mRNA expression (TPM) of 32 stage IV NSCLC patients (including LUAD and LUSC)

    OEP004524

  • PROJ Species’ functional traits and interactions drive nitrate-mediated sulfur-oxidizing community structure and functioning

    Meiying Xu, Guangdong Institute of Microbiology,2023.06.22

    Description

    Nitrate-mediated sulfur-oxidizing communities

    OEP004208