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  • PROJ Test

    Yuanhu Ju, SCBIT,2020.06.01

    Description

    test

    OEP000983

  • PROJ sample1

    development NODE, ,2021.12.29

    Description

    OEP003026

  • PROJ Genome-wide association analysis of protein coding variants in IgA nephropathy

    Ming Li, Department of Nephrology, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences,2022.12.06

    Description

    IgA nephropathy (IgAN) is a major cause of kidney failure worldwide. Here we investigated the contribution of genome-wide protein coding variants to IgAN risk by performing a three-stage exome chip-based association study in 8,529 IgAN patients and 23,224 healthy controls of Han Chinese ancestry. We discovered a novel rare nonsynonymous risk variant in VEGFA, and further sequencing of VEGFA revealed twice as many carriers of other rare variants in 2,148 IgAN cases compared to 2,732 controls. We also discovered a common nonsynonymous risk variant in PKD1L3, and the variant was shown to be associated with nearby HP gene expression and lower protein level by previous and current studies. However, a common loss-of-function mutation of PKD1L3 did not show any association, suggesting that HP is more likely to be a susceptibility gene for IgAN. Our discovery of VEGFA and HP has expanded understanding on the genetic basis of IgAN susceptibility.

    OEP003779

  • PROJ multiregion proteomics from Human liver MS-DIA

    Siyu Jing, ,2023.10.03

    Description

    To explore microenvironmental alterations in liver cancer, parenchymal and stromal tissues were extracted via laser-capture microdissection from tumors and corresponding adjacent non-tumor areas within 6 HCC patients with rich stromal components. To we divided the parenchymal region (T-P and N-P) and the stromal region (T-S and N‒S) according to locations and tissue morphology in the tumor and adjacent non-tumor area. Formalin-fixed paraffin-embedded sections were thus obtained for proteomic analysis utilizing data-independent collection (DIA) mass spectrometry (MS).

    OEP004595

  • PROJ Haplotype-resolved assemblies and variant benchmark of a Chinese Quartet

    Ying Yu, Fudan University,2022.10.05

    Description

    OEP003685

  • PROJ FUSCC_TNBC_scRNA

    Ding Ma, Fudan University Shanghai cancer center,2022.05.21

    Description

    Here, we performed single-cell RNA sequencing of pre-treatment tumor samples in 26 patients with early-stage TNBC and 6 patients with advanced TNBC to define anti-PD-1 response-related components in the tumor microenvironment. Also, we performed RNA sequencing of pre-treatment tumor samples in 60 patients with early-stage TNBC receiving neoadjuvant anti-PD1 treatment.

    OEP003394

  • PROJ JScovid19

    Zheng Lab, Fudan univerisity,2021.08.09

    Description

    OEP002590

  • PROJ mRNA expression in advanced NSCLC

    Xiaoxi Cheng, Chinese Academy of Medical Sciences,2023.09.11

    Description

    The dataset contains mRNA expression (TPM) of 32 stage IV NSCLC patients (including LUAD and LUSC)

    OEP004524

  • PROJ Species’ functional traits and interactions drive nitrate-mediated sulfur-oxidizing community structure and functioning

    Meiying Xu, Guangdong Institute of Microbiology,2023.06.22

    Description

    Nitrate-mediated sulfur-oxidizing communities

    OEP004208

  • PROJ Omics data for DLBCL patients

    Di Fu, Shanghai Jiao Tong University,2020.08.27

    Description

    OEP001143