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  • PROJ Deciphering the composition and key driver genes of invasive micropapillary carcinoma (IMPC) by multi-omics analysis and multicenter retrospective cohort

    Yaoyao Zhou, Tianjin medical university,2024.04.20

    Description

    We delved into the intrinsic cellular components and transcriptomic signatures characterizing invasive micropapillary carcinoma (IMPC).Notably, we crafted a pioneering single-cell atlas of IMPC in human breast tissue, unraveling substantial heterogeneity predominantly driven by two distinct cell subsets: epithelioid cells and interstitial cells. Pseudotime analysis unveiled unique cell trajectories for IDC-NOS cells, epithelioid IMPC cells, and interstitial IMPC cells. Of significance, we found a significant positive correlation between KRT80 expression in IMPC and clinicopathological characteristics, such as lymph node metastasis and lymphatic vessel invasion. Additionally, high KRT80 expression was associated with shorter overall survival and disease-free survival times for IMPC patients in a multicenter retrospective cohort.

    OEP005223

  • PROJ Mangrove plastisphere MAGs

    Qian Yang, CAS,2023.08.29

    Description

    OEP004489

  • PROJ WGS of RB cell lines

    Peiwei Chai, Shanghai Ninth people's hospital,2024.04.10

    Description

    The WGS of RB cell lines

    OEP005198

  • PROJ PCOS_RNA_Seq

    Chenqi Lu, Fudan University,2023.10.24

    Description

    This project collected peripheral blood samples from four PCOS and four corresponding health controls. Integrated lncRNA, miRNA, and mRNA transcriptome analysis revealed key regulatory modules for polycystic ovary syndrome (PCOS).

    OEP004667

  • PROJ The implication of the vaginal microbiome in female infertility and assisted conception outcomes

    xiuju chen, ,2024.04.14

    Description

    Infertility rates are on the rise, presenting a complex array of causative factors. Recent advancements in human microbiome and associated techniques have shed light on the potential impact of vaginal microbiota disruptions on female fertility. Our study aims to investigate differences in vaginal microbiome between fertile women and those experiencing infertility. Additionally, we aim to investigate how microbial composition in infertile population may affect the success of assisted reproduction technology (ART).

    OEP005207

  • PROJ The implication of the vaginal microbiome in female infertility and assisted conception outcomes

    xiuju chen, ,2024.04.03

    Description

    OEP005180

  • PROJ WGS of PDC

    Peiwei Chai, Shanghai Ninth people's hospital,2024.04.10

    Description

    The WGS of PDC with hydroxyurea of treatment

    OEP005197

  • PROJ Circle-seq of the retinoblastoma tissues and normal controls

    Peiwei Chai, Shanghai Ninth people's hospital,2024.04.10

    Description

    OEP005199

  • PROJ WGS of the normal controls (retina tissues)

    Peiwei Chai, Shanghai Ninth people's hospital,2024.04.12

    Description

    The cohort includes 5 samples

    OEP005203

  • PROJ WGS of the retinoblastoma

    Peiwei Chai, Shanghai Ninth people's hospital,2024.04.07

    Description

    This cohort includes 20 patients.

    OEP005189