Latest Publications

• OEP000195 Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos
  Erwei, Z., Yidi, S., Wu, W., Tanglong, Y., Wenqin, Y., & Hao, S., et al. (2018). Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos. Science.
  Science      PMID: 30819928      DOI: 10.1126/science.aav9973
• OEP000169 VCAM-1+ macrophages guide the homing of HSPCs to a vascular niche
  Dantong, L., Wenzhi, X., Mei, L., Mei, D., Jianwei, W., & Xianda, W., et al. (2018). VCAM-1+ macrophages guide the homing of HSPCs to a vascular niche. Nature.
  Nature      PMID: 30455424      DOI: 10.1038/s41586-018-0709-7
• OEP000101 Cloning of Macaque Monkeys by Somatic Cell Nuclear Transfer
  Liu Z, Cai Y, Wang Y, et al. Cloning of Macaque Monkeys by Somatic Cell Nuclear Transfer[J]. Cell, 2018, 172(4).
  Cell      PMID: 29395327      DOI: 10.1016/j.cell.2018.01.020
• OEP000104 Creating a functional single-chromosome yeast
  Shao, Y., Lu, N., Wu, Z., Cai, C., Wang, S., & Zhang, L. L., et al. (2018). Creating a functional single-chromosome yeast. Nature.
  Nature      PMID: 30069045      DOI: 10.1038/s41586-018-0382-x
• OEP000216 Structure and Degradation of Circular RNAs Regulate PKR Activation in Innate Immunity
  Liu, CX, Li X, Nan F, Jiang S, Gao X, Guo SK, & Xue W, et.al. Structure and Degradation of Circular RNAs Regulate PKR Activation in Innate Immunity. CELL.
  CELL(CELL)      PMID: 31031002      DOI: 10.1016/j.cell.2019.03.046
• OEP000277 Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis
  Zhou, C., Sun, Y., Yan, R. et al. Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis. Nature 571, 275–278 (2019).
  Nature      PMID: 31181567      DOI: 10.1038/s41586-019-1314-0
• OEP000321 Integrated Proteogenomic Characterization of HBV-Related Hepatocellular Carcinoma
  Gao Q, Zhu H, Dong L, et.al Integrated Proteogenomic Characterization of HBV-Related Hepatocellular Carcinoma. Cell. 2019 Oct 3;179(2):561-577.e22
  CELL(CELL)      PMID: 31585088      DOI: 10.1016/j.cell.2019.08.052
• OEP000320 Molecular architecture of lineage allocation and tissue organization in early mouse embryo.
  Molecular architecture of lineage allocation and tissue organization in early mouse embryo. Peng G, Suo S, Cui G, Yu F, Wang R, Chen J, Chen S, Liu Z, Chen G, Qian Y, Tam PPL, Han JJ, Jing N. Nature. 2019 Aug 7.
  Nature      PMID: 31391582      DOI: 10.1038/s41586-019-1469-8
• OEP000114 BE-PLUS: a new base editing tool with broadened editing window and enhanced fidelity
  Jiang W , Feng S, Huang S , Yu W , Li G, Yang G , Liu Y ,et al. (2018). BE-PLUS: a new base editing tool with broadened editing window and enhanced fidelity
  Cell research      PMID: 29875396      DOI: 10.1038/s41422-018-0052-4
• OEP000103 Dynamic chromosomal tuning of a novel GAU1lncing driver at chr12p13.32 accelerates tumorigenesis
  Chai P , Jia R , Jia R , et al. Dynamic chromosomal tuning of a novel GAU1 lncing driver at chr12p13.32 accelerates tumorigenesis[J]. Nucleic Acids Research, 2018, 46(12):52.
  Nucleic Acids Research      PMID: 29741668      DOI: 10.1093/nar/gky366