Latest Publications
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OEP000195
Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos
Erwei, Z., Yidi, S., Wu, W., Tanglong, Y., Wenqin, Y., & Hao, S., et al. (2018). Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos. Science.
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OEP000169
VCAM-1+ macrophages guide the homing of HSPCs to a vascular niche
Dantong, L., Wenzhi, X., Mei, L., Mei, D., Jianwei, W., & Xianda, W., et al. (2018). VCAM-1+ macrophages guide the homing of HSPCs to a vascular niche. Nature.
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OEP000101
Cloning of Macaque Monkeys by Somatic Cell Nuclear Transfer
Liu Z, Cai Y, Wang Y, et al. Cloning of Macaque Monkeys by Somatic Cell Nuclear Transfer[J]. Cell, 2018, 172(4).
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OEP000104
Creating a functional single-chromosome yeast
Shao, Y., Lu, N., Wu, Z., Cai, C., Wang, S., & Zhang, L. L., et al. (2018). Creating a functional single-chromosome yeast. Nature.
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OEP000216
Structure and Degradation of Circular RNAs Regulate PKR Activation in Innate Immunity
Liu, CX, Li X, Nan F, Jiang S, Gao X, Guo SK, & Xue W, et.al. Structure and Degradation of Circular RNAs Regulate PKR Activation in Innate Immunity. CELL.
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OEP000277
Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis
Zhou, C., Sun, Y., Yan, R. et al. Off-target RNA mutation induced by DNA base editing and its elimination by mutagenesis. Nature 571, 275–278 (2019).
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OEP000321
Integrated Proteogenomic Characterization of HBV-Related Hepatocellular Carcinoma
Gao Q, Zhu H, Dong L, et.al Integrated Proteogenomic Characterization of HBV-Related Hepatocellular Carcinoma. Cell. 2019 Oct 3;179(2):561-577.e22
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OEP000320
Molecular architecture of lineage allocation and tissue organization in early mouse embryo.
Molecular architecture of lineage allocation and tissue organization in early mouse embryo. Peng G, Suo S, Cui G, Yu F, Wang R, Chen J, Chen S, Liu Z, Chen G, Qian Y, Tam PPL, Han JJ, Jing N. Nature. 2019 Aug 7.
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OEP000114
BE-PLUS: a new base editing tool with broadened editing window and enhanced fidelity
Jiang W , Feng S, Huang S , Yu W , Li G, Yang G , Liu Y ,et al. (2018). BE-PLUS: a new base editing tool with broadened editing window and enhanced fidelity
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OEP000103
Dynamic chromosomal tuning of a novel GAU1lncing driver at chr12p13.32 accelerates tumorigenesis
Chai P , Jia R , Jia R , et al. Dynamic chromosomal tuning of a novel GAU1 lncing driver at chr12p13.32 accelerates tumorigenesis[J]. Nucleic Acids Research, 2018, 46(12):52.