Latest Publications
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OEP000515
An allosteric PGAM1 inhibitor effectively suppresses pancreatic ductal adenocarcinoma
Wen C, Huang K, Jiang L, et al. An allosteric PGAM1 inhibitor effectively suppresses pancreatic ductal adenocarcinoma. Proceedings of the National Academy of Sciences Oct 2019, 201914557.
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OEP000850
MTSS1 suppresses mammary tumor-initiating cells by enhancing RBCK1-mediated p65 ubiquitination
Cong, M., Wang, Y., Yang, Y. et al. MTSS1 suppresses mammary tumor-initiating cells by enhancing RBCK1-mediated p65 ubiquitination. Nat Cancer 1, 222–234 (2020).
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OEP000459
Comparison of cytosine base editors and development of the BEable-GPS database for targeting pathogenic SNVs
Wang Y, Gao R, Wu J, et al. Comparison of cytosine base editors and development of the BEable-GPS database for targeting pathogenic SNVs. Genome Biol. 2019 Oct 23;20(1):218.
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OEP000795
CEOP/IVE/GDP Alternating Regimen Compared with CEOP as the First-line Therapy for Newly Diagnosed Patients with Peripheral T-cell Lymphoma: Results from a Phase 2, Multi-center, Randomized, Controlled Clinical Trial
Cai, M., Cheng, S., Wang, X. et al. CEOP/IVE/GDP alternating regimen compared with CEOP as the first-line therapy for newly diagnosed patients with peripheral T cell lymphoma: results from a phase 2, multicenter, randomized, controlled clinical trial. Genome Med 12, 41 (2020).
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OEP000685
Age and Mothers: Potent Influences of Children’s Skin Microbiota
T Zhu et al. J Invest Dermatol (2019)
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OEP000877
Viral and host factors related to the clinical outcome of COVID-19
Zhang, X., Tan, Y., Ling, Y. et al. Viral and host factors related to the clinical outcome of COVID-19. Nature (2020).
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OEP000759
Genomic Profiling of Adult and Pediatric B-cell Acute Lymphoblastic Leukemia
Liu YF, Wang BY, Zhang WN, et al. Genomic Profiling of Adult and Pediatric B-cell Acute Lymphoblastic Leukemia. EBioMedicine. 2016;8:173-183.
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OEP000644
Heterogeneous immunogenomic features and distinct escape mechanisms in multifocal hepatocellular carcinoma
Dong LQ, Peng LH, Ma LJ, Liu DB, Zhang S, Luo SZ, Rao JH, Zhu HW, Yang SX, Xi SJ, Chen M, Xie FF, Li FQ, Li WH, Ye C, ... ... Zhou J, et al. Heterogeneous immunogenomic features and distinct escape mechanisms in multifocal hepatocellular carcinoma. Journal of Hepatology.
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OEP000760
Identification of fusion genes and characterization of transcriptome features in T-cell acute lymphoblastic leukemia
Chen B, Jiang L, Zhong ML, et al. Identification of fusion genes and characterization of transcriptome features in T-cell acute lymphoblastic leukemia [published correction appears in Proc Natl Acad Sci U S A. 2020 Sep 15;117(37):23192]. Proc Natl Acad Sci U S A. 2018;115(2):373-378.
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OEP000194
Alterations of gut microbiome accelerate multiple myeloma progression by increasing the relative abundances of nitrogen-recycling bacteria
Jian, X., Zhu, Y., Ouyang, J. et al. Alterations of gut microbiome accelerate multiple myeloma progression by increasing the relative abundances of nitrogen-recycling bacteria. Microbiome 8, 74 (2020).