Disorder "Diabetes Mellitus"
Found 16 records
Disorder information
Disorder name:
Diabetes Mellitus
Disoder ID:
Definition:
A group of abnormalities characterized by hyperglycemia and glucose intolerance.
Modifier statisitcs
Record:
16
Gene:
10
Variant:
16
Reference:
8
Effect type:
Expressivity(13)
,Penetrance(3)
Modifier effect:
Risk factor(12)
,Altered incidence(3)
,Altered life span(1)
| Modifier gene | Variant | Effect type | Modifier effect | Evidence | Effect | PubMed ID |
|---|---|---|---|---|---|---|
| ADRB3 | ADRB3:c.190T>C(p.Trp64Arg) | Expressivity | Risk factor | From review article | Although βAR SNPs may not directly cause disease, they appear to be risk factors for, and modifiers of, disease and the response to stress and drugs.more | more |
| ADRB2 | ADRB2:c.46A>G(p.Arg16Gly) | Expressivity | Risk factor | From review article | Although βAR SNPs may not directly cause disease, they appear to be risk factors for, and modifiers of, disease and the response to stress and drugs.more | more |
| ADRB2:c.79C>G(p.Gln27Glu) | Expressivity | Risk factor | From review article | Although βAR SNPs may not directly cause disease, they appear to be risk factors for, and modifiers of, disease and the response to stress and drugs.more | more | |
| ADRB2:T164I | Expressivity | Risk factor | From review article | Although βAR SNPs may not directly cause disease, they appear to be risk factors for, and modifiers of, disease and the response to stress and drugs.more | more | |
| ADRB1 | ADRB1:c.145A>G(p.Ser49Gly) | Expressivity | Risk factor | From review article | Although βAR SNPs may not directly cause disease, they appear to be risk factors for, and modifiers of, disease and the response to stress and drugs.more | more |
| ADRB1:c.1165G>C(p.Gly389Arg) | Expressivity | Risk factor | From review article | Although βAR SNPs may not directly cause disease, they appear to be risk factors for, and modifiers of, disease and the response to stress and drugs.more | more |