Disorder "Arrhythmia"
Found 37 records
Disorder information
Disorder name:
Arrhythmia
Disoder ID:
Definition:
Any cardiac rhythm other than the normal sinus rhythm. Such a rhythm may be either of sinus or ectopic origin and either regular or irregular. An arrhythmia may be due to a disturbance in impulse formation or conduction or both.
Modifier statisitcs
Record:
37
Gene:
15
Variant:
34
Reference:
3
Effect type:
Expressivity(37)
Modifier effect:
Risk factor(28)
,Altered severity(6)
,Altered current amplitude(2)
,Altered ectopic trigger and maintenance of AF(1)
| Modifier gene | Variant | Effect type | Modifier effect | Evidence | Effect | PubMed ID |
|---|---|---|---|---|---|---|
| ADRB3 | ADRB3:c.190T>C(p.Trp64Arg) | Expressivity | Risk factor | From review article | This genetic variance may contribute as a second genetic modifier for arrhythmia development is under current investigation.more | more |
| ADRB2 | ADRB2:c.79C>G(p.Gln27Glu) | Expressivity | Risk factor | From review article | This genetic variance may contribute as a second genetic modifier for arrhythmia development is under current investigation.more | more |
| ADRB2:c.46A>G(p.Arg16Gly) | Expressivity | Risk factor | From review article | This genetic variance may contribute as a second genetic modifier for arrhythmia development is under current investigation.more | more | |
| ADRB2:T164I | Expressivity | Risk factor | From review article | This genetic variance may contribute as a second genetic modifier for arrhythmia development is under current investigation.more | more | |
| ADRB1 | ADRB1:c.145A>G(p.Ser49Gly) | Expressivity | Risk factor | From review article | This genetic variance may contribute as a second genetic modifier for arrhythmia development is under current investigation.more | more |
| ADRB1:c.1165G>C(p.Gly389Arg) | Expressivity | Risk factor | From review article | This genetic variance may contribute as a second genetic modifier for arrhythmia development is under current investigation.more | more | |
| ADORA2B | ADORA2B:c.EEE297-299del | Expressivity | Risk factor | From review article | This genetic variance may contribute as a second genetic modifier for arrhythmia development is under current investigation.more | more |