Disorder "Hepatitis C"
Found 2 records
Disorder information
Disorder name:
Hepatitis C
Disoder ID:
Synonyms:
NANBH,Viral hepatitis C,chronic hepatitis C,hepatitis C infection,hepatitis nonA nonB
Definition:
A viral infectious disease that results_in inflammation located_in liver, has_material_basis_in Hepatitis C virus, which is transmitted_by blood from an infected person enters the body of an uninfected person. The infection has_symptom fever, has_symptom fatigue, has_symptom loss of appetite, has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, has_symptom clay-colored bowel movements, has_symptom joint pain, and has_symptom jaundice.
Modifier statisitcs
Record:
2
Gene:
1
Variant:
1
Reference:
1
Effect type:
Expressivity(2)
Modifier effect:
Altered HCV risk(1)
,Altered HCV risk and altered levels of high-density lipoprotein cholesterol(1)
| Modifier gene | Variant | Effect type | Modifier effect | Evidence | Effect | PubMed ID |
|---|---|---|---|---|---|---|
| CD81 | CD81:c.67-1543C>T | Expressivity | Altered HCV risk and altered levels of high-density lipoprotein cholesterol | HDL-c; OR=0.71, 95% CI: 0.52-0.96 | Homozygous CD81 rs708564 TT may be a genetic modifier for avoiding HCV infectionmore | more |
| CD81:c.67-1543C>T | Expressivity | Altered HCV risk | OR=0.66, 95% CI: 0.44-0.98 | Homozygous CD81 rs708564 TT may be a genetic modifier for avoiding HCV infectionmore | more |
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