Disorder "Inflammatory Bowel Disease"
Found 9 records
Disorder information
Disorder name:
Inflammatory Bowel Disease
Disoder ID:
OMIM entry:
Definition:
An intestinal disease characterized by inflammation located_in all parts of digestive tract.
Modifier statisitcs
Record:
9
Gene:
2
Variant:
7
Reference:
2
Effect type:
Expressivity(9)
Modifier effect:
Risk factor(9)
| Modifier gene | Variant | Effect type | Modifier effect | Evidence | Effect | PubMed ID |
|---|---|---|---|---|---|---|
| IL23R | IL23R:c.1+2+3+4a | Expressivity | Risk factor | P=2.22×10(-13), OR=0.360; 95% CI: (0.000–0.463) | Reduced risk of Crohn disease, psoriasis and ankylosing , protecting against inflammatory bowel diseasemore | more |
| IL23R:c.1+2+3a | Expressivity | Risk factor | P=4.22×10(4), OR=0.448; 95% CI: (0.000–0.683) | Reduced risk of Crohn disease, psoriasis and ankylosing , protecting against inflammatory bowel diseasemore | more | |
| IL23R:c.1084G>A(p.Val362Ile) | Expressivity | Risk factor | Assessment of genotype–phenotype associations and gene activity study | Reduced risk of IBDmore | more | |
| IL23R:c.1142G>A(p.Arg381Gln) | Expressivity | Risk factor | P=6.53×10(13), OR=0.330; 95% CI: (0.000–0.439) | Reduced risk of Crohn disease, psoriasis and ankylosing , protecting against inflammatory bowel diseasemore | more | |
| IL23R:c.257G>A(p.Arg86Gln) | Expressivity | Risk factor | P=0.069, OR=0.180; 95% CI: (0.000–1.125) | Reduced risk of Crohn disease, psoriasis and ankylosing , protecting against inflammatory bowel diseasemore | more | |
| IL23R:c.445G>A(p.Gly149Arg) | Expressivity | Risk factor | Assessment of genotype–phenotype associations and gene activity study | Reduced risk of IBDmore | more | |
| IL23R:c.445G>A(p.Gly149Arg) | Expressivity | Risk factor | P=0.031, OR=0.230; 95% CI: (0.000–0.879) | Reduced risk of Crohn disease, psoriasis and ankylosing , protecting against inflammatory bowel diseasemore | more | |
| IL23R:c.1084G>A(p.Val362Ile) | Expressivity | Risk factor | P=0.010, OR=0.548; 95% CI: (0.000–0.851) | Reduced risk of Crohn disease, psoriasis and ankylosing , protecting against inflammatory bowel diseasemore | more | |
| CARD9 | CARD9:c.IVS11+1G>C | Expressivity | Risk factor | Assessment of genotype–phenotype associations and gene activity study | Reduced risk of IBDmore | more |
Total 9,Each Page
,Jump To
Page