Disorder "Non-Hodgkin Lymphoma"
Found 2 records
Disorder information
Disorder name:
Non-Hodgkin Lymphoma
Disoder ID:
OMIM entry:
Definition:
A type of lymphoma characterized microscopically by the absence of multinucleated Reed-Sternberg cells.
Modifier statisitcs
Record:
2
Gene:
2
Variant:
2
Reference:
1
Effect type:
Expressivity(2)
Modifier effect:
Altered susceptibility(2)
| Modifier gene | Variant | Effect type | Modifier effect | Evidence | Effect | PubMed ID |
|---|---|---|---|---|---|---|
| TP53 | TP53:rs1042522 | Expressivity | Altered susceptibility | OR=1.73, 95% CI: 1.16–2.57, P=0.007 | The TP53 Arg72Pro and the MDM4 rs4245739 polymorphisms contribute to NHL susceptibilitymore | more |
| MDM4 | MDM4:c.*32C>A | Expressivity | Altered susceptibility | OR=0.45, 95% CI: 0.24-0.85, P=0.014 | The TP53 Arg72Pro and the MDM4 rs4245739 polymorphisms contribute to NHL susceptibilitymore | more |
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