Disorder "Primary open angle glaucoma"
Found 4 records
Disorder information
Disorder name:
Primary open angle glaucoma 
Disoder ID:
OMIM entry:
Synonyms:
chronic simple glaucoma 
Definition:
An open-angle glaucoma that is characterized by the absence of any apparent obstruction of aqueous outflow through the trabecular meshwork with gonioscopy, but often with elevated intraocular pressure. 
Modifier statisitcs
Record:
Gene:
Variant:
Reference:
Effect type:
Expressivity(4)  
Modifier effect:
Altered onset time(4)  
Modifier gene Variant Effect type Modifier effect Evidence Effect PubMed ID
COL18A1 COL18A1:rs144147445 Expressivity  Altered onset time  Pedigree analysis  genetic variation in COL15A1 and COL18A1 can modify the age of onset of both early and late onset POAG.more more
COL15A1 COL15A1:rs10519 Expressivity  Altered onset time  Pedigree analysis  genetic variation in COL15A1 and COL18A1 can modify the age of onset of both early and late onset POAG.more more
COL15A1:rs2075662 Expressivity  Altered onset time  Pedigree analysis  genetic variation in COL15A1 and COL18A1 can modify the age of onset of both early and late onset POAG.more more
COL15A1:rs61999303 Expressivity  Altered onset time  Pedigree analysis  genetic variation in COL15A1 and COL18A1 can modify the age of onset of both early and late onset POAG.more more
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