Disorder "Relapsing-Remitting Multiple Sclerosis"
Found 1 record
Disorder information
Disorder name:
Relapsing-Remitting Multiple Sclerosis 
Disoder ID:
Synonyms:
RRMS,Relapsing-remitting MS 
Definition:
A multiple sclerosis that is characterized by relapse (attacks of symptom flare-ups) followed by remission (periods of recovery). Symptoms may vary from mild to severe, and relapses and remissions may last for days or months. More than 80 percent of people who have MS begin with relapsing-remitting cycles. 
Modifier statisitcs
Record:
Gene:
Variant:
Reference:
Effect type:
Expressivity(1)  
Modifier effect:
Risk factor(1)  
Modifier gene Variant Effect type Modifier effect Evidence Effect PubMed ID
CTLA4 CTLA4:c.+49A/G(p.Thr17Ala) Expressivity  Risk factor  OR=1.36; 95% CI: 1.11-1.81; P=0.038  The CTLA4 +49 A/G and 3'UTR polymorphisms as potential modifiers of disease course in MS.more more
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