Disorder "Stomach Cancer"
Found 2 records
Disorder information
Disorder name:
Stomach Cancer
Disoder ID:
OMIM entry:
Synonyms:
Ca body - stomach,Ca lesser curvature - stomach,ca greater curvature of stomach,gastric cancer,gastric neoplasm,malignant neoplasm of body of stomach,malignant neoplasm of lesser curve of stomach,malignant tumor of body of stomach,malignant tumor of greater curve of stomach,malignant tumor of lesser curve of stomach
Definition:
A cancer arising in any part of the stomach.
Modifier statisitcs
Record:
2
Gene:
1
Variant:
2
Reference:
1
Effect type:
Expressivity(2)
Modifier effect:
Risk factor(2)
| Modifier gene | Variant | Effect type | Modifier effect | Evidence | Effect | PubMed ID |
|---|---|---|---|---|---|---|
| TGFBR1 | TGFBR1:c.97+6819A>T | Expressivity | Risk factor | OR=1.36, 95% CI: 1.14-1.63 for rs6478974 AT/AA vs. TT | We found that these two SNPs were associated with a significantly increased risk of gastric cancer in dominant models [adjusted odds ratio (OR)=1.36, 95% confidence interval (CI): 1.14-1.63 for rs6478974 AT/AA vs. TT; adjusted OR=1.26, 95% CI: 1.05-1.50 for rs10512263 CT/CC vs. TT] or additive model (adjusted OR=1.23, 95% CI: 1.08-1.40 for rs6478974).more | more |
| TGFBR1:c.98-5066T>C | Expressivity | Risk factor | Adjusted OR=1.26, 95% CI: 1.05-1.50 for rs10512263 CT/CC vs. TT | We found that these two SNPs were associated with a significantly increased risk of gastric cancer in dominant models [adjusted odds ratio (OR)=1.36, 95% confidence interval (CI): 1.14-1.63 for rs6478974 AT/AA vs. TT; adjusted OR=1.26, 95% CI: 1.05-1.50 for rs10512263 CT/CC vs. TT] or additive model (adjusted OR=1.23, 95% CI: 1.08-1.40 for rs6478974).more | more |
Total 2,Each Page
,Jump To
Page