Disorder "Carotid Stenosis"
Found 1 record
Disorder information
Disorder name:
Carotid Stenosis
Disoder ID:
Synonyms:
Stenosis, carotid artery, Carotid artery stenosis
Definition:
Carotid artery stenosis is a narrowing of the large arteries on either side of the neck that carry blood to the head, face and brain. This narrowing is usually the result of a build-up of plaque within the arteries, a condition called atherosclerosis. Stenosis can worsen over time to completely block the artery which may lead to stroke.
Modifier statisitcs
Record:
1
Gene:
1
Variant:
1
Reference:
1
Effect type:
Expressivity(1)
Modifier effect:
Risk factor(1)
Modifier gene | Variant | Effect type | Modifier effect | Evidence | Effect | PubMed ID |
---|---|---|---|---|---|---|
APOA5 | APOA5:c.-1131T>C | Expressivity | Risk factor | OR=3.69, P<0.05 | The C allele of the -1131T>C SNP in the APOA5 gene was associated with an increased risk for the development of carotid plaque in patientsmore | more |
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