Disorder "Cirrhosis"
Found 1 record
Disorder information
Disorder name:
Cirrhosis
Disoder ID:
Definition:
A chronic disorder of the liver in which liver tissue becomes scarred and is partially replaced by regenerative nodules and fibrotic tissue resulting in loss of liver function.
Modifier statisitcs
Record:
1
Gene:
1
Variant:
1
Reference:
1
Effect type:
Expressivity(1)
Modifier effect:
Risk factor(1)
| Modifier gene | Variant | Effect type | Modifier effect | Evidence | Effect | PubMed ID |
|---|---|---|---|---|---|---|
| XRCC1 | XRCC1:c.1196A>G(p.Gln399Arg) | Expressivity | Risk factor | Adjusted OR=1.82, 95% CI: 1.10-3.30 | The XRCC1 399Gln polymorphism may be a significant risk modifier for alcoholic liver cirrhosismore | more |
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