Disorder "Elevated Systolic Blood Pressure"
Found 1 record
Disorder information
Disorder name:
Elevated Systolic Blood Pressure
Disoder ID:
Definition:
Abnormal increase in systolic blood pressure.
Modifier statisitcs
Record:
1
Gene:
1
Variant:
1
Reference:
1
Effect type:
Expressivity(1)
Modifier effect:
Risk factor(1)
| Modifier gene | Variant | Effect type | Modifier effect | Evidence | Effect | PubMed ID |
|---|---|---|---|---|---|---|
| LPL | LPL:p.Ser447* | Expressivity | Risk factor | OR=0.90, 95% CI: 0.70 to 1.15 | The LPL S447X polymorphism also impacts on CHD risk through interaction with hypertension, and there was an additive action of these 2 polymorphisms and SBP on CHD riskmore | more |
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