Variant "RRM2B:variant"
Search result: 1 record
Variant information
Gene:
RRM2B 
Variant:
RRM2B:variant 
dbSNP ID:
no data 
GWAS trait:
no data 
Modifier statisitcs
Record:
1 
Disorder:
1 
Reference:
1 
Effect type:
Expressivity(1)  
Modifier effect:
Altered onset time(1)  
Detail：
  • Target disease:
    Huntington's Disease (DOID_12858)
    Effect type:
    Expressivity 
    Modifier effect:
    Altered onset time 
    Evidence:
    From review article 
    Effect:
    Associated with age at disease onset
    Reference:
    PMID29977663
    Title:
    Genetic Modifiers in Neurodegeneration.
    Species studied:
    Human
    Abstract:
    To review the evidence for genetic modifier effects in the neurodegenerative diseases Huntington's Disease (HD), Frontotemporal Lobar Degeneration (FTLD), Alzheimer's Disease (AD), and Parkinson's Disease (PD).