Methotrexate is associated with decrease expression of UGT1A8.
(References:
de Almagro et al., Biochem Pharmacol, 2011
;
Data Source:
The Comparative Toxicogenomics Database(CTD)
)
- ID
- C000469
- Class
- Drug
- Xrefs
-
DrugBank:DB00563
- Aliases
-
4-amino-10-methylfolic acid4-amino-N(10)-methylpteroylglutamic acidAmethopterinMTXN-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid
- Description
-
This compound belongs to the class of organic compounds known as glutamic acid and derivatives. These are compounds containing glutamic acid or a derivative thereof resulting from reaction of glutamic acid at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.
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- ID
- G001739
- Class
- Gene
- Xrefs
-
HGNC:12540
- Aliases
-
UGT1H
- Description
-
UDP glucuronosyltransferase family 1 member A8
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