Carvedilol

Basic Information

CAS ID: 72956-09-3
Molecular Formula: C24H26N2O4
Molecular Weight: 406.5 g/mol
Monoisotopic Mass: 406.1893 g/mol
Class: Small Molecule
Natural Product: No
Other Names: EUCARDIC 12.5 | SK&F-105517-D | EUCARDIC 6.25 | Coreg CR | CARVEDILOL | BM 14.190 | BM-14.190 | Carvedilol phosphate | BM-14-190 | COREG | EUCARDIC 25 | EUCARDIC 3.125 | COREG CR
Analysis: Drug repositioning mechanism analysis

O O NH OH O NH

Compound Structure and Identifier

InChI: InChI=1S/C24H26N2O4/c1-28-21-10-4-5-11-22(21)29-14-13-25-15-17(27)16-30-23-12-6-9-20-24(23)18-7-2-3-8-19(18)26-20/h2-12,17,25-27H,13-16H2,1H3 See All
InChI Key: OGHNVEJMJSYVRP-UHFFFAOYSA-N
Smiles: COc1ccccc1OCCNCC(O)COc2cccc3[nH]c4ccccc4c23 See All
Molfile: Download

Related Target

Related Fibrosis Property

Reference Record 1

PubMed ID 28595719 Target ID
Uniprot ID Name
Model rat Fibrosis Disease Cardiac fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Trial Record 1

ClinicalTrial ID NCT02907749 Disease Liver fibrosis
Phase Phase 4 Status Recruiting
First Received September 20, 2016 Last Verified October 10, 2017
Sponsor Changqing Yang

Trial Record 2

ClinicalTrial ID NCT03069339 Disease Liver fibrosis
Phase Not Applicable Status Recruiting
First Received March 3, 2017 Last Verified May 17, 2018
Sponsor Institute of Liver and Biliary Sciences, India

Trial Record 3

ClinicalTrial ID NCT02638415 Disease Liver fibrosis
Phase Phase 4 Status Unknown
First Received December 23, 2015 Last Verified December 23, 2015
Sponsor Shanghai Zhongshan Hospital

Trial Record 4

ClinicalTrial ID NCT01212250 Disease Liver fibrosis
Phase Not Applicable Status Recruiting
First Received September 30, 2010 Last Verified February 6, 2018
Sponsor Institute of Liver and Biliary Sciences, India

Trial Record 5

ClinicalTrial ID NCT01196507 Disease Liver fibrosis
Phase Not Applicable Status Completed
First Received September 8, 2010 Last Verified June 15, 2016
Sponsor Institute of Liver and Biliary Sciences, India

Trial Record 6

ClinicalTrial ID NCT03195634 Disease Liver fibrosis
Phase Status Not yet recruiting
First Received June 22, 2017 Last Verified June 22, 2017
Sponsor Shanghai Changzheng Hospital

Trial Record 7

ClinicalTrial ID NCT02385422 Disease Liver fibrosis
Phase Phase 4 Status Unknown
First Received March 11, 2015 Last Verified March 11, 2015
Sponsor Shanghai Zhongshan Hospital

Related Link

PubChem: 2585
ChEMBL: CHEMBL723