Praziquantel

Basic Information

CAS ID: 55268-74-1
Molecular Formula: C19H24N2O2
Molecular Weight: 312.4 g/mol
Monoisotopic Mass: 312.1838 g/mol
Class: Small Molecule
Natural Product: No
Other Names: PRAZIQUANTEL | EMBAY 8440 | Droncit | CESOL | BILTRICIDE | Cestocur | CYSTICIDE | CISTICID | EMBAY-8440
Analysis: Drug repositioning mechanism analysis

O N N O

Compound Structure and Identifier

InChI: InChI=1S/C19H24N2O2/c22-18-13-20(19(23)15-7-2-1-3-8-15)12-17-16-9-5-4-6-14(16)10-11-21(17)18/h4-6,9,15,17H,1-3,7-8,10-13H2 See All
InChI Key: FSVJFNAIGNNGKK-UHFFFAOYSA-N
Smiles: O=C(C1CCCCC1)N2CC3N(CCc4ccccc34)C(=O)C2 See All
Molfile: Download

Related Target

Related Fibrosis Property

Reference Record 1

PubMed ID 28408356 Target ID
Uniprot ID Name
Model mice Fibrosis Disease Liver fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 2

PubMed ID 28483578 Target ID
Uniprot ID Name
Model vitro,mice Fibrosis Disease Liver fibrosis
Process I
Process II HSC proliferation
Process III prevenet collagen deposition
Mechanism Targeting IFN-γ signaling and TGF-β signaling

Trial Record 1

ClinicalTrial ID NCT01260012 Disease Liver fibrosis
Phase Not Applicable Status Unknown
First Received December 15, 2010 Last Verified December 15, 2010
Sponsor Addis Ababa University

Trial Record 2

ClinicalTrial ID NCT01260012 Disease Periportal fibrosis
Phase Not Applicable Status Unknown
First Received December 15, 2010 Last Verified December 15, 2010
Sponsor Addis Ababa University

Related Link

PubChem: 4891
ChEMBL: CHEMBL976