10-Hydroxycamptothecin

Basic Information

CAS ID: 19685-09-7
Molecular Formula: C20H16N2O5
Molecular Weight: 364.4 g/mol
Monoisotopic Mass: 364.1059 g/mol
Class: Small Molecule
Natural Product: No
Other Names: 10-Hydroxycamptothecin | 10-Hydroxy Camptothecin | 10-Hydroxy-Camptothecin | 10-Hydroxycamptothecine | Hydroxycamptothecin
Analysis: Drug repositioning mechanism analysis

OH O O N OH N O

Compound Structure and Identifier

InChI: InChI=1S/C20H16N2O5/c1-2-20(26)14-7-16-17-11(5-10-6-12(23)3-4-15(10)21-17)8-22(16)18(24)13(14)9-27-19(20)25/h3-7,23,26H,2,8-9H2,1H3/t20-/m0/s1 See All
InChI Key: HAWSQZCWOQZXHI-FQEVSTJZSA-N
Smiles: CC[C@@]1(O)C(=O)OCC2=C1C=C3N(Cc4cc5cc(O)ccc5nc34)C2=O See All
Molfile: Download

Related Target

Related Fibrosis Property

Reference Record 1

PubMed ID 24681041 Target ID
Uniprot ID Name
Model vitro Fibrosis Disease Joint fibrosis
Process I
Process II cells proliferation,cells apoptosis
Process III
Mechanism

Reference Record 2

PubMed ID 28097065 Target ID
Uniprot ID Name
Model vitro,rat Fibrosis Disease Epidural fibrosis
Process I
Process II fibroblasts apoptosis
Process III prevenet collagen deposition
Mechanism Targeting NOXA expression

Related Link

PubChem: 97226
ChEMBL: CHEMBL273862