Ligustrazine

Basic Information

CAS ID: 1124-11-4
Molecular Formula: C8H12N2
Molecular Weight: 136.2 g/mol
Monoisotopic Mass: 136.1 g/mol
Class: Small Molecule
Natural Product: Yes
Other Names: 2,3,5,6-Tetramethylpyrazine | Ligustrazine | Ligustrazine Hydrochloride | 2,3,5,6-Tetramethyl-Pyrazine | Tetramethylpyrazine
Analysis: Drug repositioning mechanism analysis

N N

Compound Structure and Identifier

InChI: InChI=1S/C8H12N2/c1-5-6(2)10-8(4)7(3)9-5/h1-4H3 See All
InChI Key: FINHMKGKINIASC-UHFFFAOYSA-N
Smiles: Cc1nc(C)c(C)nc1C See All
Molfile: Download

Related Target

Related Fibrosis Property

Reference Record 1

PubMed ID 23247439 Target ID
Uniprot ID Name
Model vitro Fibrosis Disease Liver fibrosis
Process I
Process II HSCs activation,HSCs proliferation,HSCs apoptosis
Process III
Mechanism

Reference Record 2

PubMed ID 28052321 Target ID
Uniprot ID Name
Model vitro,mice,rat Fibrosis Disease Liver fibrosis
Process I
Process II HSC activation
Process III prevenet collagen deposition
Mechanism Targeting hedgehog signaling

Related Link

PubChem: 14296
ChEMBL: CHEMBL303697