Gemcitabine

Basic Information

CAS ID: 95058-81-4
Molecular Formula: C9H11F2N3O4
Molecular Weight: 263.2 g/mol
Monoisotopic Mass: 263.0718 g/mol
Class: Small Molecule
Natural Product: No
Other Names: GEMCITABINE | LY-188011 | GEMCITABINE HYDROCHLORIDE | GEMZAR | Gemzar
Analysis: Drug repositioning mechanism analysis

H2N N O N O OH OH F F

Compound Structure and Identifier

InChI: InChI=1S/C9H11F2N3O4/c10-9(11)6(16)4(3-15)18-7(9)14-2-1-5(12)13-8(14)17/h1-2,4,6-7,15-16H,3H2,(H2,12,13,17)/t4-,6-,7-/m1/s1 See All
InChI Key: SDUQYLNIPVEERB-QPPQHZFASA-N
Smiles: NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](CO)[C@@H](O)C2(F)F See All
Molfile: Download

Related Target

Related Fibrosis Property

Reference Record 1

PubMed ID 27655706 Target ID
Uniprot ID Name
Model vitro,mice Fibrosis Disease Pancreatic fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Trial Record 1

ClinicalTrial ID NCT00470340 Disease Fibrosis
Phase Phase 3 Status Terminated
First Received May 7, 2007 Last Verified May 5, 2011
Sponsor Assistance Publique - Hôpitaux de Paris

Related Link

PubChem: 60750
ChEMBL: CHEMBL888