| CAS ID: | 115939-25-8 |
| Molecular Formula: | C36H30O16 |
| Molecular Weight: | 718.6 g/mol |
| Monoisotopic Mass: | 718.1534 g/mol |
| Class: | Small Molecule |
| Natural Product: | Yes |
| Other Names: | |
| Analysis: | Drug repositioning mechanism analysis |
| InChI: | InChI=1S/C36H30O16/c37-20-6-1-16(11-24(20)41)13-27(34(45)46)50-29(44)10-5-18-3-9-23(40)33-30(18)31(32(52-33)19-4-8-22(39)26(43)15-19)36(49)51-28(35(47)48)14-17-2-7-21(38)25(42)12-17/h1-12,15,27-28,31-32,37-43H,13-14H2,(H,45,46)(H,47,48)/b10-5+/t27-,28-,31-,32+/m1/s1 | See All |
| InChI Key: | SNKFFCBZYFGCQN-PDVBOLEISA-N | |
| Smiles: | OC(=O)[C@@H](Cc1ccc(O)c(O)c1)OC(=O)\C=C\c2ccc(O)c3O[C@H]([C@H](C(=O)O[C@H](Cc4ccc(O)c(O)c4)C(=O)O)c23)c5ccc(O)c(O)c5 | See All |
| Molfile: | Download |
Reference Record 1
| PubMed ID | 27507327 | Target ID | |
| Uniprot ID | Name | ||
| Model | vitro,mice | Fibrosis Disease | Pulmonary fibrosis |
| Process I | regulate cytokines and growth factors,attenue inflammation | ||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting Nrf2/Nox4 redox balance and TGF-β1/Smad3 signaling | ||
Reference Record 2
| PubMed ID | 26637809 | Target ID | |
| Uniprot ID | Name | ||
| Model | vitro,rat | Fibrosis Disease | Liver fibrosis |
| Process I | |||
| Process II | HSCs activation | ||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting Wnt/β-catenin pathway | ||
Reference Record 3
| PubMed ID | 26257392 | Target ID | |
| Uniprot ID | Name | ||
| Model | vitro,mice | Fibrosis Disease | Liver fibrosis |
| Process I | |||
| Process II | EMT | ||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting Patched1 methylation | ||
Reference Record 4
| PubMed ID | 19474275 | Target ID | |
| Uniprot ID | Name | ||
| Model | vitro | Fibrosis Disease | Fibrosis |
| Process I | |||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | |||
| PubChem: | 11629084 |
| ChEMBL: | CHEMBL3747259 |