| CAS ID: | 96036-03-2 |
| Molecular Formula: | C17H25N3O5S |
| Molecular Weight: | 383.5 g/mol |
| Monoisotopic Mass: | 383.1515 g/mol |
| Class: | Small Molecule |
| Natural Product: | No |
| Other Names: | MEROPENEM | SM-7338 | ICI 194,660 | MERREM | Merrem i.v. |
| Analysis: | Drug repositioning mechanism analysis |
| InChI: | InChI=1S/C17H25N3O5S/c1-7-12-11(8(2)21)16(23)20(12)13(17(24)25)14(7)26-9-5-10(18-6-9)15(22)19(3)4/h7-12,18,21H,5-6H2,1-4H3,(H,24,25)/t7-,8-,9+,10+,11-,12-/m1/s1 | See All |
| InChI Key: | DMJNNHOOLUXYBV-PQTSNVLCSA-N | |
| Smiles: | C[C@@H](O)[C@@H]1[C@H]2[C@@H](C)C(=C(N2C1=O)C(=O)O)S[C@@H]3CN[C@@H](C3)C(=O)N(C)C | See All |
| Molfile: | Download |
Reference Record 1
| PubMed ID | 27132188 | Target ID | |
| Uniprot ID | Name | ||
| Model | Fibrosis Disease | Cystic fibrosis | |
| Process I | |||
| Process II | |||
| Process III | |||
| Mechanism | |||
Trial Record 1
| ClinicalTrial ID | NCT01044719 | Disease | Cystic fibrosis |
| Phase | Phase 4 | Status | Unknown |
| First Received | January 8, 2010 | Last Verified | April 13, 2010 |
| Sponsor | Imperial College London | ||
Trial Record 2
| ClinicalTrial ID | NCT01667094 | Disease | Cystic fibrosis |
| Phase | Phase 4 | Status | Active, not recruiting |
| First Received | August 17, 2012 | Last Verified | April 20, 2017 |
| Sponsor | The Alfred | ||
Trial Record 3
| ClinicalTrial ID | NCT02840136 | Disease | Cystic fibrosis |
| Phase | Not Applicable | Status | Suspended |
| First Received | July 21, 2016 | Last Verified | June 13, 2018 |
| Sponsor | University Ghent | ||
Trial Record 4
| ClinicalTrial ID | NCT01158937 | Disease | Cystic fibrosis Pulmonary Exacerbation |
| Phase | Not Applicable | Status | Terminated |
| First Received | July 8, 2010 | Last Verified | May 21, 2015 |
| Sponsor | St. Michael's Hospital, Toronto | ||
Trial Record 5
| ClinicalTrial ID | NCT01429259 | Disease | Cystic fibrosis |
| Phase | Phase 4 | Status | Completed |
| First Received | September 7, 2011 | Last Verified | March 20, 2018 |
| Sponsor | Joseph Kuti | ||
Trial Record 6
| ClinicalTrial ID | NCT01455246 | Disease | Liver fibrosis |
| Phase | Phase 2,Phase 3 | Status | Terminated |
| First Received | October 19, 2011 | Last Verified | October 15, 2014 |
| Sponsor | University of Padova | ||
Trial Record 7
| ClinicalTrial ID | NCT02048163 | Disease | Cystic fibrosis |
| Phase | Status | Withdrawn | |
| First Received | January 29, 2014 | Last Verified | February 8, 2016 |
| Sponsor | Dayton Children's Hospital | ||