Fluorofenidone

Basic Information

CAS ID: 848353-85-5
Molecular Formula: C12H10FNO
Molecular Weight: 203.2 g/mol
Monoisotopic Mass: 203.0746 g/mol
Class: Small Molecule
Natural Product: No
Other Names: Fluorofenidone
Analysis: Drug repositioning mechanism analysis

N O F

Compound Structure and Identifier

InChI: InChI=1S/C12H10FNO/c1-9-5-6-12(15)14(8-9)11-4-2-3-10(13)7-11/h2-8H,1H3 See All
InChI Key: JDZYVVUJIQYGRX-UHFFFAOYSA-N
Smiles: CC1=CN(C(=O)C=C1)c2cccc(F)c2 See All
Molfile: Download

Related Target

Target ID Name Interaction
T0665 Eukaryotic translation initiation factor 3 subunit A inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 26821114 Target ID T0665
Uniprot ID Eukaryotic translation initiation factor 3 subunit A Name Eukaryotic translation initiation factor 3 subunit A
Model vitro,rat Fibrosis Disease Pulmonary fibrosis
Process I
Process II fibroblasts proliferation,fibroblasts differetiation
Process III prevenet collagen deposition
Mechanism

Reference Record 2

PubMed ID 25989822 Target ID
Uniprot ID Name
Model vitro,human,rat Fibrosis Disease Renal fibrosis
Process I
Process II cells apoptosis
Process III
Mechanism

Reference Record 3

PubMed ID 22339859 Target ID
Uniprot ID Name
Model Fibrosis Disease Fibrosis
Process I
Process II
Process III
Mechanism

Reference Record 4

PubMed ID 21847000 Target ID
Uniprot ID Name
Model mice Fibrosis Disease Renal fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Related Link

PubChem: 11851183
ChEMBL: CHEMBL1957146