LDN 57444

Basic Information

CAS ID: 668467-91-2
Molecular Formula: C17H11Cl3N2O3
Molecular Weight: 397.7 g/mol
Monoisotopic Mass: 395.9835 g/mol
Class: Small Molecule
Natural Product: No
Other Names:
Analysis: Drug repositioning mechanism analysis

O O N O N Cl Cl Cl

Compound Structure and Identifier

InChI: InChI=1S/C17H11Cl3N2O3/c1-9(23)25-21-16-13-7-12(19)3-5-15(13)22(17(16)24)8-10-6-11(18)2-4-14(10)20/h2-7H,8H2,1H3/b21-16- See All
InChI Key: OPQRFPHLZZPCCH-PGMHBOJBSA-N
Smiles: CC(=O)O\N=C\1/C(=O)N(Cc2cc(Cl)ccc2Cl)c3ccc(Cl)cc13 See All
Molfile: Download

Related Target

Target ID Name Interaction
T0443 Ubiquitin carboxyl-terminal hydrolase isozyme L1 inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 26264933 Target ID T0443
Uniprot ID Ubiquitin carboxyl-terminal hydrolase isozyme L1 Name Ubiquitin carboxyl-terminal hydrolase isozyme L1
Model vitro,human,mice Fibrosis Disease Liver fibrosis
Process I
Process II HSCs proliferation
Process III prevenet collagen deposition
Mechanism

Related Link

PubChem: 16760696
ChEMBL: CHEMBL3407553