| CAS ID: | 50-07-7 |
| Molecular Formula: | C15H18N4O5 |
| Molecular Weight: | 334.3 g/mol |
| Monoisotopic Mass: | 334.1277 g/mol |
| Class: | Small Molecule |
| Natural Product: | No |
| Other Names: | MITOMYCIN | MYTOZYTREX | MUTAMYCIN | MITOZYTREX | MITOMYCIN C | NSC-26980 | MITOSOL |
| Analysis: | Drug repositioning mechanism analysis |
| InChI: | InChI=1S/C15H18N4O5/c1-5-9(16)12(21)8-6(4-24-14(17)22)15(23-2)13-7(18-13)3-19(15)10(8)11(5)20/h6-7,13,18H,3-4,16H2,1-2H3,(H2,17,22)/t6-,7+,13+,15-/m1/s1 | See All |
| InChI Key: | NWIBSHFKIJFRCO-WUDYKRTCSA-N | |
| Smiles: | CO[C@]12[C@H]3N[C@H]3CN1C4=C([C@H]2COC(=O)N)C(=O)C(=C(C)C4=O)N | See All |
| Molfile: | Download |
Reference Record 1
| PubMed ID | 22579993 | Target ID | |
| Uniprot ID | Name | ||
| Model | vitro | Fibrosis Disease | Eye fibrosis |
| Process I | |||
| Process II | fibroblasts proliferation | ||
| Process III | |||
| Mechanism | |||
Reference Record 2
| PubMed ID | 26254780 | Target ID | |
| Uniprot ID | Name | ||
| Model | vitro,rat | Fibrosis Disease | Epidural fibrosis |
| Process I | |||
| Process II | fibroblasts apoptosis | ||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting miR-200b and RhoE | ||
Trial Record 1
| ClinicalTrial ID | NCT00966056 | Disease | Scar |
| Phase | Phase 2 | Status | Completed |
| First Received | August 26, 2009 | Last Verified | July 8, 2011 |
| Sponsor | Karnataka Institute of Medical Sciences | ||