Berberine

Basic Information

CAS ID: 2086-83-1
Molecular Formula: C20H18NO4+
Molecular Weight: 336.4 g/mol
Monoisotopic Mass: 336.123 g/mol
Class: Small Molecule
Natural Product: Yes
Other Names: GNF-Pf-4545 | BERBERINE SULFATE | BERBERINE CHLORIDE
Analysis: Drug repositioning mechanism analysis

O O O N+ O

Compound Structure and Identifier

InChI: InChI=1S/C20H18NO4/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2/h3-4,7-10H,5-6,11H2,1-2H3/q+1 See All
InChI Key: YBHILYKTIRIUTE-UHFFFAOYSA-N
Smiles: COc1ccc2cc3c4cc5OCOc5cc4CC[n+]3cc2c1OC See All
Molfile: Download

Related Target

Related Fibrosis Property

Reference Record 1

PubMed ID 23523906 Target ID
Uniprot ID Name
Model rat Fibrosis Disease Idiopathic pulmonary fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism Targeting NF-κB

Reference Record 2

PubMed ID 24508518 Target ID
Uniprot ID Name
Model rat Fibrosis Disease Cardiac fibrosis
Process I
Process II cells apoptosis
Process III prevenet collagen deposition
Mechanism Targeting mTOR, p38 and ERK1/2 MAPK signaling

Related Link

PubChem: 2353
ChEMBL: CHEMBL295124