Tranilast

Basic Information

CAS ID: 53902-12-8
Molecular Formula: C18H17NO5
Molecular Weight: 327.3 g/mol
Monoisotopic Mass: 327.1107 g/mol
Class: Small Molecule
Natural Product: No
Other Names: MK-341 | TRANILAST
Analysis: Drug repositioning mechanism analysis

O O NH O OH O

Compound Structure and Identifier

InChI: InChI=1S/C18H17NO5/c1-23-15-9-7-12(11-16(15)24-2)8-10-17(20)19-14-6-4-3-5-13(14)18(21)22/h3-11H,1-2H3,(H,19,20)(H,21,22)/b10-8+ See All
InChI Key: NZHGWWWHIYHZNX-CSKARUKUSA-N
Smiles: COc1ccc(\C=C\C(=O)Nc2ccccc2C(=O)O)cc1OC See All
Molfile: Download

Related Target

Related Fibrosis Property

Reference Record 1

PubMed ID 18571789 Target ID
Uniprot ID Name
Model vitro,rat Fibrosis Disease Liver fibrosis
Process I
Process II HSCs activation
Process III prevenet collagen deposition
Mechanism

Reference Record 2

PubMed ID 24374452 Target ID
Uniprot ID Name
Model vitro,mice Fibrosis Disease Renal fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Related Link

PubChem: 5282230
ChEMBL: CHEMBL415324