| CAS ID: | 287714-41-4 |
| Molecular Formula: | C22H28FN3O6S |
| Molecular Weight: | 481.6 g/mol |
| Monoisotopic Mass: | 481.1683 g/mol |
| Class: | Small Molecule |
| Natural Product: | No |
| Other Names: | ROSUVASTATIN | S-4522 | ROSUVASTATIN CALCIUM | ZD-4522 | CRESTOR | ZD4522 (CALCIUM SALT) |
| Analysis: | Drug repositioning mechanism analysis |
| InChI: | InChI=1S/C22H28FN3O6S/c1-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32/h5-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30)/b10-9+/t16-,17-/m1/s1 | See All |
| InChI Key: | BPRHUIZQVSMCRT-VEUZHWNKSA-N | |
| Smiles: | CC(C)c1nc(nc(c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC(=O)O)N(C)S(=O)(=O)C | See All |
| Molfile: | Download |
Reference Record 1
| PubMed ID | 20719975 | Target ID | |
| Uniprot ID | Name | ||
| Model | rat | Fibrosis Disease | Renal fibrosis |
| Process I | attenue inflammation | ||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | |||
Reference Record 2
| PubMed ID | 24254031 | Target ID | |
| Uniprot ID | Name | ||
| Model | rat | Fibrosis Disease | Cardiac fibrosis |
| Process I | |||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | |||
Trial Record 1
| ClinicalTrial ID | NCT02428374 | Disease | Cardiac fibrosis |
| Phase | Phase 4 | Status | Recruiting |
| First Received | April 28, 2015 | Last Verified | June 11, 2015 |
| Sponsor | Federal University of São Paulo | ||
| PubChem: | 446157 |
| ChEMBL: | CHEMBL1496 |