Glutathione

Basic Information

CAS ID: 70-18-8
Molecular Formula: C10H17N3O6S
Molecular Weight: 307.3 g/mol
Monoisotopic Mass: 307.0838 g/mol
Class: Small Molecule
Natural Product: No
Other Names: GLUTATHIONE
Analysis: Drug repositioning mechanism analysis

NH2 O NH HS O NH O HO O OH

Compound Structure and Identifier

InChI: InChI=1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1 See All
InChI Key: RWSXRVCMGQZWBV-WDSKDSINSA-N
Smiles: N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(=O)O)C(=O)O See All
Molfile: Download

Related Target

Related Fibrosis Property

Reference Record 1

PubMed ID 20954832 Target ID
Uniprot ID Name
Model vitro,human Fibrosis Disease Cystic fibrosis
Process I
Process II
Process III
Mechanism Targeting myeloperoxidase

Trial Record 1

ClinicalTrial ID NCT01450267 Disease Cystic fibrosis
Phase Phase 3 Status Unknown
First Received October 12, 2011 Last Verified October 13, 2011
Sponsor Serafino A. Marsico

Trial Record 2

ClinicalTrial ID NCT03020719 Disease Cystic fibrosis
Phase Phase 2 Status Completed
First Received January 13, 2017 Last Verified December 20, 2018
Sponsor University of Minnesota - Clinical and Translational Science Institute

Trial Record 3

ClinicalTrial ID NCT02029521 Disease Cystic fibrosis
Phase Not Applicable Status Completed
First Received January 8, 2014 Last Verified February 8, 2016
Sponsor Clark Bishop

Trial Record 4

ClinicalTrial ID NCT00506688 Disease Cystic fibrosis
Phase Phase 2 Status Completed
First Received July 25, 2007 Last Verified July 10, 2012
Sponsor Mukoviszidose Institut gGmbH

Trial Record 5

ClinicalTrial ID NCT02321579 Disease Liver fibrosis
Phase Not Applicable Status Unknown
First Received December 22, 2014 Last Verified December 22, 2014
Sponsor Taichung Veterans General Hospital

Related Link

PubChem: 25246407
ChEMBL: CHEMBL1543