KNK437

Basic Information

CAS ID: 218924-25-5
Molecular Formula: C13H11NO4
Molecular Weight: 245.2 g/mol
Monoisotopic Mass: 245.0688 g/mol
Class: Small Molecule
Natural Product: No
Other Names:
Analysis: Drug repositioning mechanism analysis

O N O O O

Compound Structure and Identifier

InChI: InChI=1S/C13H11NO4/c15-7-14-4-3-10(13(14)16)5-9-1-2-11-12(6-9)18-8-17-11/h1-2,5-7H,3-4,8H2/b10-5- See All
InChI Key: LZGGUFLRKIMBDQ-YHYXMXQVSA-N
Smiles: O=CN1CC\C(=C\c2ccc3OCOc3c2)\C1=O See All
Molfile: Download

Related Target

Target ID Name Interaction
T0961 HSP70 inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 20542874 Target ID T0961
Uniprot ID HSP70 Name HSP70
Model mice Fibrosis Disease Cardiac fibrosis
Process I attenue inflammation
Process II fibroblasts differentiation,cells apoptosis
Process III prevenet collagen deposition
Mechanism

Related Link

PubChem: 9859662
ChEMBL: CHEMBL1240927