Eflornithine

Basic Information

CAS ID: 66640-93-5
Molecular Formula: C6H12F2N2O2
Molecular Weight: 182.2 g/mol
Monoisotopic Mass: 182.0867 g/mol
Class: Small Molecule
Natural Product: No
Other Names: Eflornithine HCl | VANIQA | DIFLUROMETHYLORNITHINE | MDL 71,782 A | DFMO HCL | DL-alpha-Difluoromethylornithine hydrochloride | EFLORNITHINE | ORNIDYL | EFLORNITHINE HYDROCHLORIDE | Vaniqa | Ornidyl | Eflornithine Hydrocloride
Analysis: Drug repositioning mechanism analysis

H2N NH2 F F O OH

Compound Structure and Identifier

InChI: InChI=1S/C6H12F2N2O2/c7-4(8)6(10,5(11)12)2-1-3-9/h4H,1-3,9-10H2,(H,11,12) See All
InChI Key: VLCYCQAOQCDTCN-UHFFFAOYSA-N
Smiles: NCCCC(N)(C(F)F)C(=O)O See All
Molfile: Download

Related Target

Target ID Name Interaction
T1028 Ornithine decarboxylase inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 19960215 Target ID T1028
Uniprot ID Ornithine decarboxylase Name Ornithine decarboxylase
Model vitro Fibrosis Disease Cardiac fibrosis
Process I
Process II cells apoptosis
Process III
Mechanism

Related Link

PubChem: 3009
ChEMBL: CHEMBL830