JNK Inhibitor VIII

Basic Information

CAS ID: 894804-07-0
Molecular Formula: C18H20N4O4
Molecular Weight: 356.4 g/mol
Monoisotopic Mass: 356.1485 g/mol
Class: Small Molecule
Natural Product: No
Other Names:
Analysis: Drug repositioning mechanism analysis

O N NH O O O NH2 N

Compound Structure and Identifier

InChI: InChI=1S/C18H20N4O4/c1-4-26-18-13(10-19)14(20)9-16(22-18)21-17(23)8-11-7-12(24-2)5-6-15(11)25-3/h5-7,9H,4,8H2,1-3H3,(H3,20,21,22,23) See All
InChI Key: KQMPRSZTUSSXND-UHFFFAOYSA-N
Smiles: CCOc1nc(NC(=O)Cc2cc(OC)ccc2OC)cc(N)c1C#N See All
Molfile: Download

Related Target

Related Fibrosis Property

Reference Record 1

PubMed ID 19782079 Target ID
Uniprot ID Name
Model vitro,mice Fibrosis Disease Liver fibrosis
Process I attenue inflammation
Process II HSCs activation,HSCs proliferation
Process III prevenet collagen deposition
Mechanism

Related Link

PubChem: 11624601
ChEMBL: CHEMBL210618