Voriconazole

Basic Information

CAS ID: 137234-62-9
Molecular Formula: C16H14F3N5O
Molecular Weight: 349.3 g/mol
Monoisotopic Mass: 349.115 g/mol
Class: Small Molecule
Natural Product: No
Other Names: VORICONAZOLE | VFEND | UK-109,496
Analysis: Drug repositioning mechanism analysis

N N F OH N N N F F

Compound Structure and Identifier

InChI: InChI=1S/C16H14F3N5O/c1-10(15-14(19)5-20-7-22-15)16(25,6-24-9-21-8-23-24)12-3-2-11(17)4-13(12)18/h2-5,7-10,25H,6H2,1H3/t10-,16+/m0/s1 See All
InChI Key: BCEHBSKCWLPMDN-MGPLVRAMSA-N
Smiles: C[C@@H](c1ncncc1F)[C@](O)(Cn2cncn2)c3ccc(F)cc3F See All
Molfile: Download

Related Target

Target ID Name Interaction
T0464 Cytochrome P450 3A4 Other Interaction

Related Fibrosis Property

Reference Record 1

PubMed ID 19302272 Target ID T0464
Uniprot ID Cytochrome P450 3A4 Name Cytochrome P450 3A4
Model human Fibrosis Disease Cystic fibrosis
Process I
Process II
Process III
Mechanism

Trial Record 1

ClinicalTrial ID NCT01576315 Disease Cystic fibrosis
Phase Phase 2 Status Completed
First Received April 12, 2012 Last Verified April 12, 2016
Sponsor Rennes University Hospital

Related Link

PubChem: 71616
ChEMBL: CHEMBL638