| CAS ID: | 9005-49-6 |
| Molecular Formula: | C26H42N2O37S5 |
| Molecular Weight: | 1134.9 g/mol |
| Monoisotopic Mass: | 1134.007 g/mol |
| Class: | Small Molecule |
| Natural Product: | No |
| Other Names: | Heparin |
| Analysis: | Drug repositioning mechanism analysis |
| InChI: | InChI=1S/C26H42N2O37S5/c1-4(30)27-7-9(31)13(6(56-23(7)39)3-55-67(43,44)45)58-26-19(65-70(52,53)54)12(34)16(20(62-26)22(37)38)60-24-8(28-66(40,41)42)15(63-68(46,47)48)14(5(2-29)57-24)59-25-18(64-69(49,50)51)11(33)10(32)17(61-25)21(35)36/h5-20,23-26,28-29,31-34,39H,2-3H2,1H3,(H,27,30)(H,35,36)(H,37,38)(H,40,41,42)(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54) | See All |
| InChI Key: | HTTJABKRGRZYRN-UHFFFAOYSA-N | |
| Smiles: | CC(=O)NC1C(C(C(OC1O)COS(=O)(=O)O)OC2C(C(C(C(O2)C(=O)O)OC3C(C(C(C(O3)CO)OC4C(C(C(C(O4)C(=O)O)O)O)OS(=O)(=O)O)OS(=O)(=O)O)NS(=O)(=O)O)O)OS(=O)(=O)O)O | See All |
| Molfile: | Download |
Reference Record 1
| PubMed ID | 28821136 | Target ID | |
| Uniprot ID | Name | ||
| Model | mice | Fibrosis Disease | Pulmonary fibrosis |
| Process I | |||
| Process II | fibroblasts proliferation | ||
| Process III | prevenet collagen deposition | ||
| Mechanism | |||
Reference Record 2
| PubMed ID | 18351636 | Target ID | |
| Uniprot ID | Name | ||
| Model | human | Fibrosis Disease | Cystic fibrosis |
| Process I | |||
| Process II | |||
| Process III | |||
| Mechanism | |||
Reference Record 3
| PubMed ID | 17827252 | Target ID | |
| Uniprot ID | Name | ||
| Model | human | Fibrosis Disease | Cystic fibrosis |
| Process I | attenue inflammation | ||
| Process II | |||
| Process III | |||
| Mechanism | |||
Trial Record 1
| ClinicalTrial ID | NCT02271295 | Disease | Liver fibrosis |
| Phase | Phase 3 | Status | Suspended |
| First Received | October 22, 2014 | Last Verified | February 27, 2018 |
| Sponsor | Assistance Publique - Hôpitaux de Paris | ||
Trial Record 2
| ClinicalTrial ID | NCT02708628 | Disease | Scar |
| Phase | Not Applicable | Status | Completed |
| First Received | March 15, 2016 | Last Verified | October 4, 2016 |
| Sponsor | Suleymaniye Birth And Women's Health Education And Research Hospital | ||
Trial Record 3
| ClinicalTrial ID | NCT02247414 | Disease | Liver fibrosis |
| Phase | Phase 4 | Status | Completed |
| First Received | September 25, 2014 | Last Verified | November 6, 2017 |
| Sponsor | Yangzhou University | ||
Trial Record 4
| ClinicalTrial ID | NCT02238444 | Disease | Liver fibrosis |
| Phase | Phase 4 | Status | Recruiting |
| First Received | September 12, 2014 | Last Verified | January 1, 2019 |
| Sponsor | Yangzhou University | ||
| PubChem: | |
| ChEMBL: | CHEMBL1909300 |