Rolipram

Basic Information

CAS ID: 61413-54-5
Molecular Formula: C16H21NO3
Molecular Weight: 275.4 g/mol
Monoisotopic Mass: 275.1521 g/mol
Class: Small Molecule
Natural Product: No
Other Names: ZK 62 711 | ROLIPRAM | ZK-62771
Analysis: Drug repositioning mechanism analysis

O O NH O

Compound Structure and Identifier

InChI: InChI=1S/C16H21NO3/c1-19-14-7-6-11(12-9-16(18)17-10-12)8-15(14)20-13-4-2-3-5-13/h6-8,12-13H,2-5,9-10H2,1H3,(H,17,18) See All
InChI Key: HJORMJIFDVBMOB-UHFFFAOYSA-N
Smiles: COc1ccc(cc1OC2CCCC2)C3CNC(=O)C3 See All
Molfile: Download

Related Target

Target ID Name Interaction
T0429 cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor
T0430 cAMP-specific 3',5'-cyclic phosphodiesterase 4D inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 16254133 Target ID T0430
Uniprot ID cAMP-specific 3',5'-cyclic phosphodiesterase 4D Name cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Model rat Fibrosis Disease Intestinal fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 2

PubMed ID 16254133 Target ID T0429
Uniprot ID cAMP-specific 3',5'-cyclic phosphodiesterase 4B Name cAMP-specific 3',5'-cyclic phosphodiesterase 4B
Model rat Fibrosis Disease Intestinal fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Related Link

PubChem: 5092
ChEMBL: CHEMBL63