BX471

Basic Information

CAS ID: 217645-70-0
Molecular Formula: C21H24ClFN4O3
Molecular Weight: 434.9 g/mol
Monoisotopic Mass: 434.1521 g/mol
Class: Small Molecule
Natural Product: No
Other Names: BX-741 | BX-471
Analysis: Drug repositioning mechanism analysis

N F N O O Cl NH O H2N

Compound Structure and Identifier

InChI: InChI=1S/C21H24ClFN4O3/c1-14-11-26(12-15-2-5-17(23)6-3-15)8-9-27(14)20(28)13-30-19-7-4-16(22)10-18(19)25-21(24)29/h2-7,10,14H,8-9,11-13H2,1H3,(H3,24,25,29)/t14-/m1/s1 See All
InChI Key: XQYASZNUFDVMFH-CQSZACIVSA-N
Smiles: C[C@@H]1CN(Cc2ccc(F)cc2)CCN1C(=O)COc3ccc(Cl)cc3NC(=O)N See All
Molfile: Download

Related Target

Target ID Name Interaction
T0093 C-C chemokine receptor type 1 antagonist

Related Fibrosis Property

Reference Record 1

PubMed ID 14747380 Target ID T0093
Uniprot ID C-C chemokine receptor type 1 Name C-C chemokine receptor type 1
Model vitro,mice Fibrosis Disease Renal fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 2

PubMed ID 15716328 Target ID T0093
Uniprot ID C-C chemokine receptor type 1 Name C-C chemokine receptor type 1
Model vitro,mice Fibrosis Disease Renal fibrosis
Process I attenue inflammation
Process II
Process III
Mechanism

Related Link

PubChem: 512282
ChEMBL: CHEMBL232656